DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and hgfac

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	XP_002939269.3	Gene:	hgfac / 100485696	XenbaseID:	XB-GENE-940012	Length:	595	Species:	Xenopus tropicalis

Alignment Length:	377	Identity:	108/377 - (28%)
Similarity:	165/377 - (43%)	Gaps:	94/377 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   159 PRG----TVCRGPDTKPGNCVEIKECASLLNELRSRSQDATFANFLRASNAVCQNKGTQVCCPTG 219
            |:|    ..||.||..     ||..| .|:|:        ...::...|...|::||.:|.....
Frog   279 PKGLGSHPYCRSPDDD-----EIPWC-YLMND--------RLVSWEHCSIPKCRDKGRRVIMQED 329

  Fly   220 QGITNTTPAPSQIVPKNTDEIPRRLLNVEEGCGSTVGYFKKIVGGEVSRKGAWPWIALLGYDDPS 284
            .    ..|||.:...|:...:..|               .:|:||..:..|:.||:|.:..
Frog   330 A----VVPAPPKCGKKHEKRVVAR---------------GRILGGNSALPGSHPWVAGIYI---- 371

  Fly   285 GSPFKCGGTLITARHVLTAAHCI-----RQDLQFVRLGEH--DLSTD-TETGHVDINIARYVSHP 341
            |:.| |.|:||....|::||||.     :..::.| ||:|  :.:|| |:|..|:    ||:.:.
Frog   372 GNYF-CAGSLIQPCWVVSAAHCFADSPSKSKIRVV-LGQHFFNQTTDVTQTFEVE----RYIFYD 430

  Fly   342 DYN--RRNGRSDMAILYLER----NVEFTSKIAPICLPHTANLRQKSYVGYMPF-------VAGW 393
            .|:  :|| ..|:.::.|:|    ..:.|..:..||||..:          .||       :|||
Frog   431 KYSVFKRN-EHDIVLIKLKRINNACAKKTQFVQTICLPDVS----------APFADDHHCQIAGW 484

  Fly   394 GKTMEGG-ESAQVLNELQIPIYDNKVC--VQSYAKEKRYFSADQFDKAVLCAGVLSGGKDTCQGD 455
            |:..|.. |.||.|.|..:|:..:..|  .:.|..|   .|.:.|     |||......|:||||
Frog   485 GRMHEDSTEYAQNLQEAIVPLVPDNKCSSPEIYGAE---ISENMF-----CAGYFDCTIDSCQGD 541

  Fly   456 SGGPLMLPEPYQGQLRFYLIGVVSYGIGCARPNVPGVYSSTQYFMDWIIQQV 507
            |||||...:....    ||.|:||:|.||...|.||||:....::|||.:::
Frog   542 SGGPLACEKDKIS----YLWGIVSWGEGCGNHNKPGVYTKVSNYVDWINRKI 589

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855	14/51 (27%)
		Tryp_SPc	260..503	CDD:214473	85/266 (32%)
		Tryp_SPc	261..503	CDD:238113	85/265 (32%)
hgfac	XP_002939269.3	FN2	52..98	CDD:238019
		EGF_CA	109..145	CDD:238011
		FN1	147..185	CDD:238018
		KR	235..319	CDD:294073	13/53 (25%)
		Tryp_SPc	351..585	CDD:214473	85/266 (32%)
		Tryp_SPc	352..588	CDD:238113	87/268 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910