DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and tmprss11f

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	XP_004911133.1	Gene:	tmprss11f / 100379970	XenbaseID:	XB-GENE-1012399	Length:	427	Species:	Xenopus tropicalis

Alignment Length:	387	Identity:	103/387 - (26%)
Similarity:	163/387 - (42%)	Gaps:	106/387 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   181 ASLLNELRSRSQDATFANFLRASNAVCQNKGTQV--------------CCPTGQGI-----TNTT 226
            |.:...|.|..:|:...|...:|..:..:.|:.:              ...|.|||     .||:
Frog    77 AKIAKVLDSAYEDSELKNQYNSSQVISLSPGSVIPVFVLLFNFVNNGSSASTVQGIFVENMKNTS 141

  Fly   227 PAPSQIVPKNTDEIPRRLLNVEE----------------------------GCGSTVG---YFKK 260
                    |...::.:..|::.|                            .||  :|   ...:
Frog   142 --------KTGFDVDQSSLHLSEISSSDAQNLLYSVPSTTTAYTTTAADFTACG--IGGPSVSNR 196

  Fly   261 IVGGEVSRKGAWPW---IALLGYDDPSGSPFKCGGTLITARHVLTAAHCIRQDLQFVRLGEHDLS 322
            ||||..:..|:|||   :.|||       ...||.:|:....::.||||.            |::
Frog   197 IVGGTNAGLGSWPWQASLRLLG-------SHTCGASLLNDTWLVAAAHCF------------DMN 242

  Fly   323 TDTETGHV-----------DINIARYVSHPDYNRRNGRSDMAILYLERNVEFTSKIAPICLPHTA 376
            .|..:..|           :..|.:.:.:..|...|.|:|:|:|.|...:.|||.|.|:|||..:
Frog   243 ADANSWTVVLGTINVYSGSEFKIEKIIIYEGYTSHNHRNDIALLKLFTPLNFTSIIRPVCLPEAS 307

  Fly   377 NLRQKSYVGYMPFVAGWGKTMEGGESAQVLNELQIPIYDNKVCVQSYAKEKRYFSADQFDKAVLC 441
            ::...   |...::.|||...:||.::|||.:.::.|.::..|..|.......:      .:::|
Frog   308 DIFPD---GSSCYITGWGALTDGGSASQVLQQAEVKIINSDTCSSSQMYGGLIY------PSMIC 363

  Fly   442 AGVLSGGKDTCQGDSGGPLMLPEPYQGQLRFYLIGVVSYGIGCARPNVPGVYSSTQYFMDWI 503
            ||..:|..|:|||||||||:..:  .|  |:.|||:||:|.|||.||.|||||...|..:||
Frog   364 AGYATGQIDSCQGDSGGPLVTLK--SG--RWVLIGIVSFGYGCALPNKPGVYSRITYLRNWI 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855	7/48 (15%)
		Tryp_SPc	260..503	CDD:214473	82/256 (32%)
		Tryp_SPc	261..503	CDD:238113	82/255 (32%)
tmprss11f	XP_004911133.1	SEA	48..148	CDD:396113	14/78 (18%)
tmprss11f	XP_004911133.1	Tryp_SPc	197..421	CDD:238113	82/255 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000