Protein Alignment Ras64B and RRAS

DIOPT Version :9

• Sequence 1: NP_523917.2
• Gene: Ras64B / 38494
• FlyBaseID: FBgn0003206
• Length: 192
• Species: Drosophila melanogaster
• Sequence 2: NP_006261.1
• Gene: RRAS / 6237
• HGNCID: 10447
• Length: 218
• Species: Homo sapiens
• Alignment Length: 191
• Identity: 123/191 - (64%)
• Similarity: 148/191 - (77%)
• Gaps: 2/191 - (1%)

  Fly     4 QTYKLVVVGGGGVGKSAITIQFIQSYFVTDYDPTIEDSYTKQCNIDDVPAKLDILDTAGQEEFSA 68
            :|:||||||||||||||:||||||||||:||||||||||||.|::|.:||:||||||||||||.|
Human    28 ETHKLVVVGGGGVGKSALTIQFIQSYFVSDYDPTIEDSYTKICSVDGIPARLDILDTAGQEEFGA 92

  Fly    69 MREQYMRSGEGFLLVFALNDHSSFDEIPKFQRQILRVKDRDEFPMLMVGNKCDLKHQQQVSLEEA 133
            |||||||:|.|||||||:||..||:|:.|...|||||||||:||:::||||.||:.|:||...||
Human    93 MREQYMRAGHGFLLVFAINDRQSFNEVGKLFTQILRVKDRDDFPVVLVGNKADLESQRQVPRSEA 157

  Fly   134 QNTSRNLMIPYIECSAKLRVNVDQAFHELVRIVRKFQIAERPFI--EQDYKKKGKRKCCLM 192
            .....:..:.|.|.|||||:|||:||.:|||.|||:|..|.|..  ....||.|...|.|:
Human   158 SAFGASHHVAYFEASAKLRLNVDEAFEQLVRAVRKYQEQELPPSPPSAPRKKGGGCPCVLL 218

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ras64B	NP_523917.2	M_R_Ras_like	4..167	CDD:133345	112/162 (69%)
RRAS	NP_006261.1	M_R_Ras_like	28..191	CDD:133345	112/162 (69%)
		Effector region	58..66		7/7 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165146907
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0395
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S596
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1259506at2759
OrthoFinder	1	1.000	-	-		FOG0000092
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24070
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1068
SonicParanoid	1	1.000	-	-		X1567
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	10	9.790