DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ras64B and hrasa

DIOPT Version :9

Sequence 1:	NP_523917.2	Gene:	Ras64B / 38494	FlyBaseID:	FBgn0003206	Length:	192	Species:	Drosophila melanogaster
Sequence 2:	NP_001017623.1	Gene:	hrasa / 550286	ZFINID:	ZDB-GENE-050417-95	Length:	189	Species:	Danio rerio

Alignment Length:	169	Identity:	101/169 - (59%)
Similarity:	129/169 - (76%)	Gaps:	1/169 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 MQTYKLVVVGGGGVGKSAITIQFIQSYFVTDYDPTIEDSYTKQCNIDDVPAKLDILDTAGQEEFS 67
            |..|||||||.|||||||:|||.||::||.:|||||||||.||..||.....|||||||||||:|
Zfish     1 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYS 65

  Fly    68 AMREQYMRSGEGFLLVFALNDHSSFDEIPKFQRQILRVKDRDEFPMLMVGNKCDLKHQQQVSLEE 132
            |||:||||:|||||.|||:|:..||::|.:::.||.||||.|:.||::|||||||. .:.|...:
Zfish    66 AMRDQYMRTGEGFLCVFAINNTKSFEDIHQYREQIKRVKDSDDVPMVLVGNKCDLP-ARIVDTRQ 129

  Fly   133 AQNTSRNLMIPYIECSAKLRVNVDQAFHELVRIVRKFQI 171
            ||..:|:..||:||.|||.|..|:.||:.|||.:|:.::
Zfish   130 AQELARSYGIPFIETSAKTRQGVEDAFYTLVREIRQHKM 168

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ras64B	NP_523917.2	M_R_Ras_like	4..167	CDD:133345	99/162 (61%)
hrasa	NP_001017623.1	H_N_K_Ras_like	3..164	CDD:133338	99/161 (61%)
hrasa	NP_001017623.1	RAS	16..166	CDD:214541	89/150 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1259506at2759
OrthoFinder	1	1.000	-	-		FOG0000092
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100217
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1068
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.850