Protein Alignment Ras64B and DIRAS2

DIOPT Version :10

• Sequence 1: NP_523917.2
• Gene: Ras64B / 38494
• FlyBaseID: FBgn0003206
• Length: 192
• Species: Drosophila melanogaster
• Sequence 2: NP_060064.2
• Gene: DIRAS2 / 54769
• HGNCID: 19323
• Length: 199
• Species: Homo sapiens
• Alignment Length: 196
• Identity: 67/196 - (34%)
• Similarity: 108/196 - (55%)
• Gaps: 5/196 - (2%)

  Fly     2 QMQTYKLVVVGGGGVGKSAITIQFIQSYFVTDYDPTIEDSYTKQCNIDDVPAKLDILDTAGQEEF 66
            |...|::.|.|.||||||::.::|::..|...|.||:||:|.:..:.|.....|.|.||.|..:|
Human     4 QSNDYRVAVFGAGGVGKSSLVLRFVKGTFRESYIPTVEDTYRQVISCDKSICTLQITDTTGSHQF 68

  Fly    67 SAMREQYMRSGEGFLLVFALNDHSSFDEIPKFQRQILRVK-DRDEFPMLMVGNKCDLKHQQQVSL 130
            .||:...:..|..|:||:::....|.:|:.....||..:| |.:..|:::||||||....::|..
Human    69 PAMQRLSISKGHAFILVYSITSRQSLEELKPIYEQICEIKGDVESIPIMLVGNKCDESPSREVQS 133

  Fly   131 EEAQNTSRNLMIPYIECSAKLRVNVDQAFHELVRIVRK----FQIAERPFIEQDYKKKGKRKCCL 191
            .||:..:|.....::|.||||..||.:.|.||:.:.::    .||..:...:|..|:|.|.||.:
Human   134 SEAEALARTWKCAFMETSAKLNHNVKELFQELLNLEKRRTVSLQIDGKKSKQQKRKEKLKGKCVI 198

  Fly   192 M 192
            |
Human   199 M 199

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ras64B	NP_523917.2	M_R_Ras_like	4..167	CDD:133345	57/163 (35%)
DIRAS2	NP_060064.2	ARHI_like	7..170	CDD:206711	57/162 (35%)
		Effector region. /evidence=ECO:0000255	36..44		5/7 (71%)