DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ras64B and Rap1b

DIOPT Version :9

Sequence 1:	NP_523917.2	Gene:	Ras64B / 38494	FlyBaseID:	FBgn0003206	Length:	192	Species:	Drosophila melanogaster
Sequence 2:	NP_077777.1	Gene:	Rap1b / 215449	MGIID:	894315	Length:	184	Species:	Mus musculus

Alignment Length:	192	Identity:	92/192 - (47%)
Similarity:	132/192 - (68%)	Gaps:	10/192 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 MQTYKLVVVGGGGVGKSAITIQFIQSYFVTDYDPTIEDSYTKQCNIDDVPAKLDILDTAGQEEFS 67
            |:.|||||:|.|||||||:|:||:|..||..|||||||||.||..:|.....|:||||||.|:|:
Mouse     1 MREYKLVVLGSGGVGKSALTVQFVQGIFVEKYDPTIEDSYRKQVEVDAQQCMLEILDTAGTEQFT 65

  Fly    68 AMREQYMRSGEGFLLVFALNDHSSFDEIPKFQRQILRVKDRDEFPMLMVGNKCDLKHQQQVSLEE 132
            |||:.||::|:||.||:::...|:|:::...:.|||||||.|:.||::|||||||:.::.|..|:
Mouse    66 AMRDLYMKNGQGFALVYSITAQSTFNDLQDLREQILRVKDTDDVPMILVGNKCDLEDERVVGKEQ 130

  Fly   133 AQNTSRNL-MIPYIECSAKLRVNVDQAFHELVR-IVRKFQIAERPFIEQDYKKKGKRKCCLM 192
            .||.:|.. ...::|.|||.::||::.|::||| |.||..:..        |.:.|..|.|:
Mouse   131 GQNLARQWNNCAFLESSAKSKINVNEIFYDLVRQINRKTPVPG--------KARKKSSCQLL 184

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ras64B	NP_523917.2	M_R_Ras_like	4..167	CDD:133345	85/164 (52%)
Rap1b	NP_077777.1	Rap1	3..167	CDD:133375	85/163 (52%)
		Interaction with KRIT1. /evidence=ECO:0000250	25..67		24/41 (59%)
		Effector region. /evidence=ECO:0000305	32..40		7/7 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0395
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000092
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100217
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1068
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.740