DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ras64B and krasl

DIOPT Version :9

Sequence 1:	NP_523917.2	Gene:	Ras64B / 38494	FlyBaseID:	FBgn0003206	Length:	192	Species:	Drosophila melanogaster
Sequence 2:	XP_004920180.1	Gene:	krasl / 100485959	XenbaseID:	XB-GENE-22063560	Length:	226	Species:	Xenopus tropicalis

Alignment Length:	193	Identity:	105/193 - (54%)
Similarity:	142/193 - (73%)	Gaps:	7/193 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 MQTYKLVVVGGGGVGKSAITIQFIQSYFVTDYDPTIEDSYTKQCNIDDVPAKLDILDTAGQEEFS 67
            |..|||||||.|||||||:|||.||::||.:|||||||||.||..||.....|||||||||||:|
Frog     1 MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAGQEEYS 65

  Fly    68 AMREQYMRSGEGFLLVFALNDHSSFDEIPKFQRQILRVKDRDEFPMLMVGNKCDLKHQQQVSLEE 132
            |||:||||:|||||.|||:|:..||::|..::.||.||||.::.||::|||||||. .:.|..::
Frog    66 AMRDQYMRTGEGFLCVFAINNTKSFEDIHHYREQIKRVKDSEDVPMVLVGNKCDLP-SRTVDTKQ 129

  Fly   133 AQNTSRNLMIPYIECSAKLRVNVDQAFHELVRIVRKFQIAERPFIEQDYKKKG---KRKCCLM 192
            ||:.:|:..||:||.|||.|..|:.||:.|||.:|::::.:   :.::.|..|   .:||.:|
Frog   130 AQDLARSYGIPFIETSAKTRQRVEDAFYTLVREIRQYRLKK---MSKEEKTPGCVKVKKCRVM 189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ras64B	NP_523917.2	M_R_Ras_like	4..167	CDD:133345	98/162 (60%)
krasl	XP_004920180.1	H_N_K_Ras_like	3..164	CDD:133338	98/161 (61%)
krasl	XP_004920180.1	RAS	16..166	CDD:214541	88/150 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1259506at2759
OrthoFinder	1	1.000	-	-		FOG0000092
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1068
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.950