Protein Alignment Rop and SLY1

DIOPT Version :9

• Sequence 1: NP_001261404.1
• Gene: Rop / 38493
• FlyBaseID: FBgn0004574
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_010475.1
• Gene: SLY1 / 851770
• SGDID: S000002597
• Length: 666
• Species: Saccharomyces cerevisiae
• Alignment Length: 656
• Identity: 139/656 - (21%)
• Similarity: 263/656 - (40%)
• Gaps: 153/656 - (23%)

  Fly    39 WRVLVVDKLGMRMVSACTKMHEISAEGITLVEDINKKREPLPTMDAIYLITPSDESVRGLIRDFE 103
            |:||::|......:|:..:::::...|||:...|.:.|.|||.:.|||.::|:.|::..::.|.:
Yeast    53 WKVLILDIKSTATISSVLRVNDLLKAGITVHSLIKQDRSPLPDVPAIYFVSPTKENIDIIVNDLK 117

  Fly   104 NPARPMYRYAHVFFTEVCPEELFNDLCKSCA----AGKIKTLKEINIAFLPYECQVFSLDSPDTF 164
            :   ..|...::.||...|..|..||.:..:    :.|||.:.:..:.|:..|.::|||:..:.:
Yeast   118 S---DKYSEFYINFTSSLPRNLLEDLAQQVSITGKSDKIKQVYDQYLDFIVTEPELFSLEISNAY 179

  Fly   165 QCLYSPAFASIRSKHIERIAEQIATLCA-----------TLGEYPNVRYRSDWDRNIDLAASVQQ 218
            ..|..|          :...|:|..|||           |:...|.:|........| :|..:..
Yeast   180 LTLNDP----------KTTEEEITGLCANIADGLFNTVLTINSIPIIRAAKGGPAEI-IAEKLGT 233

  Fly   219 KL-----DAYKADDATMGEGPEKARSQLLILDRGFDCVSPLLHELTLQAMAYDLLPIVNDVYRY- 277
            ||     :...:..:|:.......|..|:||||..|..|...|....|.|.:|:..:..:....
Yeast   234 KLRDFVINTNSSSTSTLQGNDSLERGVLIILDRNIDFASMFSHSWIYQCMVFDIFKLSRNTVTIP 298

  Fly   278 ----------TPGPNQPDKEVLLDENDDLWVELRH-------EHI-AVVST--QVTQNLKKFTDS 322
                      |.......|:..::.||..|:|..|       |:: |.::|  :....:.:.|..
Yeast   299 LESKENGTDNTTAKPLATKKYDIEPNDFFWMENSHLPFPEAAENVEAALNTYKEEAAEITRKTGV 363

  Fly   323 KRMGSADKSSMRD---LSQMIKKMPQYQKELSKYSTHLHLAEDCMKSYQN-YVDKLCRVEQD--- 380
            ..:...|.:|..|   :.:::||:|:...:.:...||:::....:...:: .:|....||||
Yeast   364 TNISDLDPNSNNDTVQIQEVVKKLPELTAKKNTIDTHMNIFAALLSQLESKSLDTFFEVEQDPGS 428

  Fly   381 -------LAMGTDAEGEKIKDHMRNIVPILLDA----------NVSNYDKVR---IIALYVMIKN 425
                   |.:..|.:...::|.:|:.:.:.|.:          ||.||.|..   |.||..:.|
Yeast   429 TKTRSRFLDILKDGKTNNLEDKLRSFIVLYLTSTTGLPKDFVQNVENYFKENDYDINALKYVYK- 492

  Fly   426 GISEENLTKLFTHAQLSPKDQDM---------VRNLSCLGINVIADSR------------KKQYS 469
                  |.:....:.:|.:::.:         ..||:..||..:.:.:            ||  .
Yeast   493 ------LREFMQLSNMSLQNKSLEDGSDSAFKPSNLTLSGIYGLTEGKLQGGVGSLISGIKK--L 549

  Fly   470 VPRKERTTESTYQMSRWTPVIKDIMEDCIEDKLDLRHFPFLEGRAQNTN---YHAPTSARYGHWH 531
            :|.|:            |..|.::: |.|.|.|:..     :...:.|:   |..|...|..|..
Yeast   550 LPEKK------------TIPITNVV-DAIMDPLNSS-----QKNLETTDSYLYIDPKITRGSHTR 596

  Fly   532 KDKGQAQVKNVPRLIVFIVGGVSMSEMRCAYEVTNAVRNW---------EVLVGSSHILSPEIFL 587
            |.|.|:..|:    :||:|||.:..|.:       .::.|         :|:.||:.|.:|..||
Yeast   597 KPKRQSYNKS----LVFVVGGGNYLEYQ-------NLQEWAHSQLHNPKKVMYGSTAITTPAEFL 650

  Fly   588 SDLGSL 593
            :::..|
Yeast   651 NEISRL 656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rop	NP_001261404.1	Sec1	40..583	CDD:395791	134/643 (21%)
SLY1	NP_010475.1	SEC1	11..661	CDD:227487	139/656 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810