Protein Alignment Rop and stxbp1

DIOPT Version :9

• Sequence 1: NP_001261404.1
• Gene: Rop / 38493
• FlyBaseID: FBgn0004574
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_001072521.1
• Gene: stxbp1 / 779976
• XenbaseID: XB-GENE-945143
• Length: 604
• Species: Xenopus tropicalis
• Alignment Length: 592
• Identity: 375/592 - (63%)
• Similarity: 465/592 - (78%)
• Gaps: 18/592 - (3%)

  Fly     3 LKVLVGQKLMNEVVKYKPPPPKKQGVTSAAGAGGMEWRVLVVDKLGMRMVSACTKMHEISAEGIT 67
            ||.:||:|:|::|::    ..||:|          ||:|||||:|.|||:|:|.||.:|..||||
 Frog     6 LKAVVGEKIMHDVIR----KVKKKG----------EWKVLVVDQLSMRMLSSCCKMTDIMTEGIT 56

  Fly    68 LVEDINKKREPLPTMDAIYLITPSDESVRGLIRDFENPARPMYRYAHVFFTEVCPEELFNDLCKS 132
            :||||||:|||:|:::|:||||||::||..||.||::|....||.||||||:.||:.|||:|.||
 Frog    57 IVEDINKRREPIPSLEAVYLITPSEKSVHSLISDFKDPPSSKYRAAHVFFTDSCPDTLFNELVKS 121

  Fly   133 CAAGKIKTLKEINIAFLPYECQVFSLDSPDTFQCLYSPAFASIRSKHIERIAEQIATLCATLGEY 197
            ..:..||||.||||||||||.||||||.||:|...|||..|.:::..:||:|||||||||||.||
 Frog   122 RTSKMIKTLTEINIAFLPYESQVFSLDYPDSFHSFYSPHKAQMKNPILERLAEQIATLCATLKEY 186

  Fly   198 PNVRYRSDWDRNIDLAASVQQKLDAYKADDATMGEGPEKARSQLLILDRGFDCVSPLLHELTLQA 262
            |.||||.|:..|..|:..:|.|||||||||.||||||:||||||:|||||||..||:|||||.||
 Frog   187 PAVRYRGDYKDNAMLSQLIQDKLDAYKADDPTMGEGPDKARSQLIILDRGFDPASPILHELTFQA 251

  Fly   263 MAYDLLPIVNDVYRY-TPG-PNQPDKEVLLDENDDLWVELRHEHIAVVSTQVTQNLKKFTDSKRM 325
            |:|||||:.||||:| |.| .:|..|||||||:|||||.|||:|||.||.:||::||.|:.||||
 Frog   252 MSYDLLPVENDVYKYETSGIGDQRMKEVLLDEDDDLWVTLRHKHIAEVSQEVTRSLKDFSASKRM 316

  Fly   326 GSADK-SSMRDLSQMIKKMPQYQKELSKYSTHLHLAEDCMKSYQNYVDKLCRVEQDLAMGTDAEG 389
            .:.|| ::|||||||:|||||||||||||||||||||||||.||..|||||||||||||||||||
 Frog   317 NTGDKVTTMRDLSQMLKKMPQYQKELSKYSTHLHLAEDCMKHYQGTVDKLCRVEQDLAMGTDAEG 381

  Fly   390 EKIKDHMRNIVPILLDANVSNYDKVRIIALYVMIKNGISEENLTKLFTHAQLSPKDQDMVRNLSC 454
            |||||.||.|||||||.|||.|||:|||.||:.:||||:||||.||..|||:.|:|.:::.|::.
 Frog   382 EKIKDPMRAIVPILLDGNVSTYDKIRIINLYIFLKNGITEENLNKLIQHAQIPPEDSEIITNMAH 446

  Fly   455 LGINVIADSRKKQYSVP-RKERTTESTYQMSRWTPVIKDIMEDCIEDKLDLRHFPFLEGRAQNTN 518
            ||:.:|.||..::.|.| ||||.:|.|||:||||||:||||||.|:||||.:|:|::..|:..:.
 Frog   447 LGVPIITDSTLRRRSKPDRKERISEQTYQLSRWTPVVKDIMEDTIDDKLDTKHYPYISTRSSASF 511

  Fly   519 YHAPTSARYGHWHKDKGQAQVKNVPRLIVFIVGGVSMSEMRCAYEVTNAVRNWEVLVGSSHILSP 583
            .....|||||||||:|...:.:..||||:||:|||::|||||||||:.|...||||:||:|||:|
 Frog   512 STTAVSARYGHWHKNKAPGEYRAGPRLIIFILGGVALSEMRCAYEVSQANGKWEVLIGSTHILTP 576

  Fly   584 EIFLSDL 590
            ..||.||
 Frog   577 TKFLEDL 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rop	NP_001261404.1	Sec1	40..583	CDD:395791	358/546 (66%)
stxbp1	NP_001072521.1	Sec1	29..576	CDD:366407	358/546 (66%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	720	1.000	Domainoid score	I115
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2382
Inparanoid	1	1.050	738	1.000	Inparanoid score	I602
OMA	1	1.010	-	-		QHG53928
OrthoDB	1	1.010	-	-		D289675at33208
OrthoFinder	1	1.000	-	-		FOG0000914
OrthoInspector	1	1.000	-	-		oto104066
Panther	1	1.100	-	-	LDO	PTHR11679
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2284
SonicParanoid	1	1.000	-	-		X527
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.110