Protein Alignment Rop and vps45

DIOPT Version :9

• Sequence 1: NP_001261404.1
• Gene: Rop / 38493
• FlyBaseID: FBgn0004574
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_001072504.1
• Gene: vps45 / 779959
• XenbaseID: XB-GENE-961682
• Length: 570
• Species: Xenopus tropicalis
• Alignment Length: 615
• Identity: 141/615 - (22%)
• Similarity: 249/615 - (40%)
• Gaps: 120/615 - (19%)

  Fly    25 KQGVTSAAGAGGMEWRVLVVDKLGMRMVSACTKMHEISAEGITLVEDINK-KREPLPTMDAIYLI 88
            ||.|:......|...:||::||....:||......||..:.:.|.|.|:. .||.:..:.||..:
 Frog     8 KQYVSKMIEDSGPGMKVLLMDKETTSVVSMVYTQSEILQKEVYLFERIDSTNRESMKHLKAICFL 72

  Fly    89 TPSDESVRGLIRDFENPARPMYRYAHVFFTEVCPEELFNDLCKSCAAGKIKTLKEINIAFLPYEC 153
            .|:.|:|..||::..   ||.|....::|:.|..:.....|.::.....:..::|....::....
 Frog    73 RPTKENVEYLIKELR---RPKYSVYFLYFSNVISKSDVKSLAEADEQEVVAEVQEFYGDYIAVNP 134

  Fly   154 QVFSLDSPDTFQCLYSPAFASIRSKHIERIAEQIATLCATLGEYPNVRYRSDWDRNIDLAASVQQ 218
            .||||:....:|.....|.      |:.|..:.:..|..:|.:.|.:||:...|....||..|:|
 Frog   135 HVFSLNIVGCYQGRNWDAV------HLYRTTQGLTALLLSLKKCPMIRYQLSSDMAKRLAEGVKQ 193

  Fly   219 KL-DAYKADDATMGEGPEKARSQLLILDRGFDCVSPLLHELTLQAMAYDLLPIVN---DVYRYTP 279
            .: ..|:..:....|.|    ..||||||..|.::|||::.|.|||.:::|.|.|   |:.| .|
 Frog   194 VITKEYELFEFRRTEVP----PLLLILDRSDDAITPLLNQWTYQAMVHEMLGINNNRIDLSR-VP 253

  Fly   280 GPNQPDKEVLLD-ENDDLWVELRHEHIAVVSTQVTQNLKKFTDSKRMGSADKSSMRDLSQMIKKM 343
            |.::..|||:|. |||:.:....:.:...:.|.:...::.|...|..|.....|:.|:...::..
 Frog   254 GISKDLKEVVLSAENDEFYANNMYLNFGEIGTNIKNLMEDFQKKKPKGQQKLESISDMKAFVENY 318

  Fly   344 PQYQK-------------ELSKYSTHLHLAEDCMKSYQNYVDKLCRVEQDLAMGTDAEGEKIKDH 395
            ||::|             |||:..:..||.|            :..|||:||...|.     .:.
 Frog   319 PQFKKMSGTVSKHVTVVGELSRLVSERHLME------------VSEVEQELACQNDH-----SNA 366

  Fly   396 MRNIVPILLDANVSNYDKVRIIALYVMIKNGISEENLTKLFTHAQL------------------- 441
            ::|:..:|.:..::..|..|::.||.:.....|...|:.|....::
 Frog   367 LQNVKRLLQNQRLAELDATRLVMLYALHYERHSSNALSSLLNDLRVRGVSEKYRRLVSAVVEYGG 431

  Fly   442 ---------SPKDQDMVRNLSCLGINVIADSRKKQYSVPRKERTTESTYQMSRWTPVIKDIMEDC 497
                     ||||...:......|:                 :..|:.|  ::..|.:.|.::..
 Frog   432 KRVRGSDLFSPKDAVAITKQFFKGL-----------------KGVENVY--TQHQPFLLDTLDQL 477

  Fly   498 IEDKLDLRHFPFLEGRAQNTNYHAPTSARYGHWHKDKGQAQVKNVPRLIVFIVGGVSMSEMRCAY 562
            |:.||....:|:|          .|.:.|      |:.|       .:|||:|||.:..|....|
 Frog   478 IKGKLKDNLYPYL----------GPNTLR------DRPQ-------DIIVFMVGGATYEEAFAVY 519

  Fly   563 EVTNAVRNWEVLVGSSHILSPEIFLSDLGS 592
            .:........:::|.:.|.:.:.||.::.|
 Frog   520 NLNRTTPGVRIVLGGTAIHNTKSFLEEVQS 549

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rop	NP_001261404.1	Sec1	40..583	CDD:395791	134/589 (23%)
vps45	NP_001072504.1	Sec1	23..539	CDD:279352	134/588 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910