Protein Alignment Rop and Vps33a

DIOPT Version :9

• Sequence 1: NP_001261404.1
• Gene: Rop / 38493
• FlyBaseID: FBgn0004574
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_084205.3
• Gene: Vps33a / 77573
• MGIID: 1924823
• Length: 598
• Species: Mus musculus
• Alignment Length: 628
• Identity: 123/628 - (19%)
• Similarity: 239/628 - (38%)
• Gaps: 153/628 - (24%)

  Fly     7 VGQKLMNEVVKYKPPPPKKQGVTSAAGAGGMEWRVLVVDKLGMRMVSACTKMHEISAEGITLVED 71
            |...::.|.|:.:    .::.:...||:..:.|...:....|:....:..|.||:. :..||
Mouse    10 VNLNVLREAVRRE----LREFLDKCAGSKAIVWDEYLTGPFGLIAQYSLLKEHEVE-KMFTL--- 66

  Fly    72 INKKREPLPTMDA---IYLITPS------------DESVRGLIRDFENPARPMYRYAHVFFTE-- 119
               |...||..|.   |:|:.|.            .|..||..|||           |:.|..
Mouse    67 ---KGSRLPAADVKNIIFLVRPRLELMDIIAENVLSEDRRGPTRDF-----------HILFVPRR 117

  Fly   120 --VCPEELFNDLCKSCAAGKIKTLKEINIAFLPYECQVFSLDSPDTFQCLYSPAFASIRSKHIER 182
              :| |:...||   ...|.....:|.::..:|::..:.|::|...|:..|...    ....:..
Mouse   118 SLLC-EQRLKDL---GVLGSFIHREEYSLDLIPFDGDLLSMESEGAFKECYLEG----DQTSLYH 174

  Fly   183 IAEQIATLCATLGEYPNVRYRSDWDRNIDLAASVQQKLDAYKADDATMGEGPEKARSQLLILDRG 247
            .|:.:.||.|..|..|.:..:.:..|.: ....|:.|.:...:.::..     .....||:|||.
Mouse   175 AAKGLMTLQALYGTIPQIFGKGECARQV-ANMMVRMKREFTGSQNSVF-----PVFDNLLLLDRN 233

  Fly   248 FDCVSPLLHELTLQAMAYDLLPIVNDVYRYTP-------------GPNQPD--KEVLLDENDDLW 297
            .|.::||..:||.:.:..::..|.|...:..|             |.:.|.  |::.|:..::|:
Mouse   234 VDLLTPLASQLTYEGLIDEIYGIQNSYVKLPPEKFAPKKQGGGSGGKDLPTEAKKLQLNSAEELY 298

  Fly   298 VELRHEHIAVVSTQVTQNLKKFT-------DSKRMGSADKSSMRDLSQMIKKMPQYQKELSKYST 355
            .|:|.::...|.:.:::..|..:       ::|.:|        ::.|.:.::|..|......:.
Mouse   299 AEIRDKNFNAVGSVLSKKAKIISAAFEERHNAKTVG--------EIKQFVSQLPHMQAARGSLAN 355

  Fly   356 HLHLAE---DCMKSYQNYVDKLCRVEQDLAMGTDAEGEKIKDHMRNIV----PILLDANVSNYDK 413
            |..:||   |...| :::.||| .|||:...|.|.  :|:..::.:.:    |::         |
Mouse   356 HTSIAELIKDVTTS-EDFFDKL-TVEQEFMSGIDT--DKVNSYIEDCIAQKHPLI---------K 407

  Fly   414 V-RIIALYVMIKNGISEENL---------TKLFTHAQLSPKDQDMVRNLSCLGINVIADSRKKQY 468
            | |::.|..:..:|:.::.|         |..:.|..       .:.||...|:.......:..|
Mouse   408 VLRLVCLQSVCNSGLKQKVLDYYRREILQTYGYEHIL-------TLNNLEKAGLLKAQTGGRNNY 465

  Fly   469 SVPRK-----------ERTTESTYQMSRWTPVIKDIME-------DCIEDKLDLRHFPFLEGRAQ 515
            ...||           :..|:.:|..|.:.|:...:.:       ..||:.|.:...|..|.|..
Mouse   466 PTIRKTLRLWMDDVNEQNPTDISYVYSGYAPLSVRLAQLLSRPGWRSIEEVLRILPGPHFEERQP 530

  Fly   516 NTNYHAPTSARYGHWHKDKGQAQVKNVPRLIVFIVGGVSMSEM 558
                 .||..:.   .:..|:.:|     .:||.:|||:.:|:
Mouse   531 -----LPTGLQK---KRQPGENRV-----TLVFFLGGVTFAEI 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rop	NP_001261404.1	Sec1	40..583	CDD:395791	117/595 (20%)
Vps33a	NP_084205.3	Sec1	34..586	CDD:279352	118/600 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810