Protein Alignment Rop and Vps45

DIOPT Version :9

• Sequence 1: NP_001261404.1
• Gene: Rop / 38493
• FlyBaseID: FBgn0004574
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_742069.1
• Gene: Vps45 / 64516
• RGDID: 621267
• Length: 570
• Species: Rattus norvegicus
• Alignment Length: 619
• Identity: 139/619 - (22%)
• Similarity: 259/619 - (41%)
• Gaps: 115/619 - (18%)

  Fly    25 KQGVTSAAGAGGMEWRVLVVDKLGMRMVSACTKMHEISAEGITLVEDI-NKKREPLPTMDAIYLI 88
            ||.::......|...:||::||....:||......||..:.:.|.|.| ::.||.:..:.||..:
  Rat     8 KQYISKMIEDSGPGMKVLLMDKETTGIVSMVYTQSEILQKEVYLFERIDSQNREIMKHLKAICFL 72

  Fly    89 TPSDESVRGLIRDFENPARPMYRYAHVFFTEVCPEELFNDLCKSCAAGKIKTLKEINIAFLPYEC 153
            .|:.|:|..||::..   ||.|....::|:.|..:.....|.::.....:..::|....::....
  Rat    73 RPTKENVDSLIQELR---RPKYSIYFIYFSNVISKSDVKSLAEADEQEVVAEVQEFYGDYIAVNP 134

  Fly   154 QVFSLDSPDTFQCL----YSPAFASIRSKHIERIAEQIATLCATLGEYPNVRYRSDWDRNIDLAA 214
            .:|||   :...|.    :.||       .:.|..:.:..|..:|.:.|.:||:...:....|..
  Rat   135 HLFSL---NILGCCQGRNWDPA-------QLSRTTQGLTALLLSLKKCPMIRYQLSSEAAKRLGE 189

  Fly   215 SVQQKLD-AYKADDATMGEGPEKARSQLLILDRGFDCVSPLLHELTLQAMAYDLLPIVN---DVY 275
            .|:|.:. .|:..:....|.|    ..||||||..|.::|||::.|.|||.::||.|.|   |:.
  Rat   190 CVKQVISKEYELFEFRRTEVP----PLLLILDRCDDAITPLLNQWTYQAMVHELLGINNNRIDLS 250

  Fly   276 RYTPGPNQPDKEVLLD-ENDDLWVELRHEHIAVVSTQVTQNLKKFTDSKRMGSADK-SSMRDLSQ 338
            | .||.::..:||:|. |||:.:....:.:.|.:.:.: :||.:....||.....| .|:.|:..
  Rat   251 R-VPGISKDLREVVLSAENDEFYANNMYLNFAEIGSNI-KNLMEDFQKKRPKEQQKLESIADMKA 313

  Fly   339 MIKKMPQYQKELSKYSTHLHLAEDCMK--SYQNYVDKLCRVEQDLAMGTDAEGEKIKDHMRNIVP 401
            .::..||::|.....|.|:.:..:..:  |.:|.:: :..|||:||...|....     ::|:..
  Rat   314 FVENYPQFKKMSGTVSKHVTVVGELSRLVSERNLLE-VSEVEQELACQNDHSSA-----LQNVKR 372

  Fly   402 ILLDANVSNYDKVRIIALYVMIKNGISEENLTKLFTHAQ-------------------------- 440
            :|.:..|:.:|.||::.||.:.....|..:|..|....:
  Rat   373 LLQNPKVTEFDAVRLVMLYALHYERHSSNSLPGLIVDLRSKGVAEKYRKLVSAVVEYGGKRVRGS 437

  Fly   441 --LSPKDQDMVRNLSCLGINVIADSRKKQYSVPRKERTTESTYQMSRWTPVIKDIMEDCIEDKLD 503
              .||||...:......|:                 :..|:.|  ::..|.:.:.::..|:.||.
  Rat   438 DLFSPKDAVAITKQFLKGL-----------------KGVENVY--TQHQPFLHETLDHLIKGKLK 483

  Fly   504 LRHFPFLEGRAQNTNYHAPTSARYGHWHKDKGQAQVKNVPR-LIVFIVGGVSMSEMRCAYEVTNA 567
            ...:|:|                        |.:.:::.|: :|||::||.:..|....|.:...
  Rat   484 ENLYPYL------------------------GPSTLRDRPQDIIVFVIGGATYEEALTVYNLNRT 524

  Fly   568 VRNWEVLVGSSHILSPEIFL-----SDLGSLSKE 596
            .....:::|.:.|.:.:.||     |.|.|.|:|
  Rat   525 TPGVRIVLGGTTIHNTKSFLEEVLASGLHSRSRE 558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rop	NP_001261404.1	Sec1	40..583	CDD:395791	129/584 (22%)
Vps45	NP_742069.1	Sec1	23..539	CDD:395791	129/583 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810