Protein Alignment Rop and vps45

DIOPT Version :9

• Sequence 1: NP_001261404.1
• Gene: Rop / 38493
• FlyBaseID: FBgn0004574
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_001243585.1
• Gene: vps45 / 561653
• ZFINID: ZDB-GENE-060503-526
• Length: 568
• Species: Danio rerio
• Alignment Length: 596
• Identity: 135/596 - (22%)
• Similarity: 263/596 - (44%)
• Gaps: 86/596 - (14%)

  Fly    25 KQGVTSAAGAGGMEWRVLVVDKLGMRMVSACTKMHEISAEGITLVEDI-NKKREPLPTMDAIYLI 88
            ||.::....:.|...:||::||....:||......||..:.:.|.|.| ::.|:.:..:.||..:
Zfish     8 KQYISKMIESSGPGMKVLLMDKETTSIVSVVYTQSEILQKEVYLFERIDSQNRDNMKHLKAICFL 72

  Fly    89 TPSDESVRGLIRDFENPARPMYRYAHVFFTEVCPEELFNDLCKSCAAGKIKTLKEINIAFLPYEC 153
            .|:.|:|..||::..   ||.|....::|:.|..:.....|.::.....:..::|....|:....
Zfish    73 RPTKENVEHLIQELR---RPKYSVYFIYFSNVISKSEVKALAEADEQEVVAEVQEFYGDFIAVNP 134

  Fly   154 QVFSLDSPDTFQ-CLYSPAFASIRSKHIERIAEQIATLCATLGEYPNVRYRSDWDRNIDLAASVQ 217
            .:|||:.....: ..:.|:.       :.|:.:.:.::..:|.:.|.:||:...|.:..||.||:
Zfish   135 HLFSLNLQGVSRGRSWEPSV-------LPRVTQGLTSVLLSLKKCPMIRYQLSSDMSKRLAESVK 192

  Fly   218 QKL-DAYKADDATMGEGPEKARSQLLILDRGFDCVSPLLHELTLQAMAYDLLPIVN---DVYRYT 278
            |.: ..|:..|....|.|    ..||||||..|.::|||::.|.|||.::||.:.|   |:.| .
Zfish   193 QIITKEYELFDFRKTEVP----PLLLILDRSDDAITPLLNQWTYQAMVHELLGLNNNRIDLSR-V 252

  Fly   279 PGPNQPDKEVLLD-ENDDLWVELRHEHIAVVSTQVTQNLKKFTDSKRMGSADKSSMRDLSQMIKK 342
            ||.::..:||:|. |||:.:....:.:...:.|.:...::.|...|........|:.|:...::.
Zfish   253 PGISKDLREVVLSAENDEFYANNLYLNFGEIGTNIKNLMEDFQKKKPKDQQKLESISDMKAFVEN 317

  Fly   343 MPQYQKELSKYSTHLHLAEDCMKSY-QNYVDKLCRVEQDLAMGTDAEGEKIKDHMRNIVPILLDA 406
            .||::|.....|.|:.:..:..:.. :..:.::..|||:||...|....:     :.:..:|...
Zfish   318 YPQFKKMSGTVSKHVTVVGELSRLVSERQLMEVSEVEQELACQNDHSNAQ-----QMLRRLLQSP 377

  Fly   407 NVSNYDKVRIIALYV-----------------MIKNGISEENLTKLFTHAQLS-----PKDQDMV 449
            .:|..|.||::.||.                 :.:.|:||.:  :...||.:.     .:..|::
Zfish   378 RLSEIDAVRLVMLYALRYEKHSSSILPSLMEELNRKGVSERH--RKMVHAVVEYGGKRIRGSDLI 440

  Fly   450 RNLSCLGINVIADSRKKQYSVPRKERTTESTYQMSRWTPVIKDIMEDCIEDKLDLRHFPFLEGRA 514
            .....:.|.       ||:.  :..:..|:.|  ::..|::.|.::..|:.:|....||:|
Zfish   441 TPTDAVSIT-------KQFF--KGLKGVENVY--TQHQPLLHDTLDQLIKGRLKDSQFPYL---- 490

  Fly   515 QNTNYHAPTSARYGHWHKDKGQAQVKNVPRLIVFIVGGVSMSEMRCAYEVTNAVRNWEVLVGSSH 579
                  .|:|.|      |:.|       .:||||:||.:..|....|.:...:....:::|.:|
Zfish   491 ------GPSSLR------DRPQ-------DIIVFIIGGATYEEALTVYNLNRTMPGVRIVLGGTH 536

  Fly   580 ILSPEIFLSDL 590
            |.:.:.||.::
Zfish   537 IHNTKSFLEEV 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rop	NP_001261404.1	Sec1	40..583	CDD:395791	130/572 (23%)
vps45	NP_001243585.1	Sec1	23..539	CDD:279352	130/571 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810