Protein Alignment Rop and stxbp3

DIOPT Version :10

• Sequence 1: NP_523916.2
• Gene: Rop / 38493
• FlyBaseID: FBgn0004574
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_001015972.1
• Gene: stxbp3 / 548726
• XenbaseID: XB-GENE-963836
• Length: 589
• Species: Xenopus tropicalis
• Alignment Length: 597
• Identity: 261/597 - (43%)
• Similarity: 398/597 - (66%)
• Gaps: 26/597 - (4%)

  Fly     3 LKVLVGQKLMNEVVKYKPPPPKKQGVTSAAGAGGMEWRVLVVDKLGMRMVSACTKMHEISAEGIT 67
            ||..|.||:..||:    ...:|          |.||::|::|....:::::|.||.::..||||
 Frog     9 LKSTVWQKIKTEVL----DDCRK----------GDEWKILLLDHFTTKLLTSCCKMTDLLQEGIT 59

  Fly    68 LVEDINKKREPLPTMDAIYLITPSDESVRGLIRDFENPARPMYRYAHVFFTEVCPEELFNDLCKS 132
            :|||:.|||:|:..|.|||.|:|:::||..|:.||.:.:...|:.|:|:|::|||:.|||.| ||
 Frog    60 VVEDLFKKRQPVEHMKAIYFISPNEKSVDCLVNDFNSKSASKYKAAYVYFSDVCPDSLFNKL-KS 123

  Fly   133 CAAGKIKTLKEINIAFLPYECQVFSLDSPDTFQCLYSPAFASIRSKHIERIAEQIATLCATLGEY 197
            |....||..|||:|:|.|.|.|||.|:.|..|..||||..|..:...|:.||:||.||||||.|.
 Frog   124 CHPKTIKRCKEISISFFPKESQVFLLNVPKAFHLLYSPDKAVDKETAIQTIAQQIVTLCATLEEN 188

  Fly   198 PNVRYRSD-WDRNIDLAASVQQKL-DAYKADDATMGEGPEKARSQLLILDRGFDCVSPLLHELTL 260
            |.|||:.: .|...:||..|:::| ..||.|:....:.  |.:|||||:|||||..|.:|||||.
 Frog   189 PGVRYKKEPLDNAEELANLVEEQLVQYYKMDEKDQFKA--KTQSQLLIVDRGFDPFSTILHELTF 251

  Fly   261 QAMAYDLLPIVNDVYRY-TPGPNQPDKEVLLDENDDLWVELRHEHIAVVSTQVTQNLKKFTDSKR 324
            |||.||||||.||:|:| |......|||..|||:|:|||::||:|||.|..::.:.:|:.:.||:
 Frog   252 QAMVYDLLPIENDIYKYRTESALAKDKEARLDESDELWVKIRHKHIANVLEEIPKLVKEISSSKK 316

  Fly   325 MGSADKSSMRDLSQMIKKMPQYQKELSKYSTHLHLAEDCMKSYQNYVDKLCRVEQDLAMGTDAEG 389
             .:....|:..|:.::||||..:|::.|.:.||.||||||:.::..::|||:.|||||:|:||||
 Frog   317 -ETEGNISISKLADIMKKMPHIRKQIGKQTLHLSLAEDCMQKFRGRLEKLCKAEQDLALGSDAEG 380

  Fly   390 EKIKDHMRNIVPILLDANVSNYDKVRIIALYVMIKNGISEENLTKLFTHAQLSPKDQDMVRNLSC 454
            :|:|||||.::|||:..::.||||:|.|.||:.::||.|:|||.:|.|||::. ...|:::|...
 Frog   381 QKVKDHMRVLLPILISNDLDNYDKIRAILLYIFVENGTSQENLDRLITHAKIE-GGGDVLKNWKY 444

  Fly   455 LGINVIADSRKKQYSVPRKERTTESTYQMSRWTPVIKDIMEDCIEDKLDLRHFPFLEGRAQNTNY 519
            ||:.::..|.:::.:  |::|:.|.|:|:|||||:|||::||.:|:|||.:.:|:........|.
 Frog   445 LGVPIVPKSTQRRPA--RRDRSKEETFQLSRWTPIIKDVIEDTMENKLDSKEWPYCSECPAAWNG 507

  Fly   520 HAPTSARYGHWHKDKGQAQVKNVPRLIVFIVGGVSMSEMRCAYEVTNAVRNWEVLVGSSHILSPE 584
            ....|||  ..|....:.:.|||.|||:|::||::.||:||||||:.|.:..:|::||:||::|:
 Frog   508 SGAVSAR--QKHNTISRDERKNVSRLIIFVIGGITYSEIRCAYEVSQANKFVQVIIGSTHIITPK 570

  Fly   585 IFLSDLGSLSKE 596
            ..|.|:.:|:||
 Frog   571 TMLDDVKNLTKE 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rop	NP_523916.2	Sec1	40..589	CDD:460020	246/551 (45%)
stxbp3	NP_001015972.1	Sec1	32..575	CDD:460020	246/551 (45%)