Protein Alignment Rop and sec1

DIOPT Version :9

• Sequence 1: NP_001261404.1
• Gene: Rop / 38493
• FlyBaseID: FBgn0004574
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_588226.1
• Gene: sec1 / 2538850
• PomBaseID: SPCC584.05
• Length: 693
• Species: Schizosaccharomyces pombe
• Alignment Length: 573
• Identity: 162/573 - (28%)
• Similarity: 293/573 - (51%)
• Gaps: 33/573 - (5%)

  Fly    38 EWRVLVVDKLGMRMVSACTKMHEISAEGITLVEDINKKREPLPTMDAIYLITPSDESVRGLIRDF 102
            :|:||:||.....:::....:|.:..|.|..||.:...|.|..:.:|:|::...::.|..:::|.
pombe    23 KWKVLIVDTKTADIINHFITIHSLLEEKIAAVEILENPRTPNSSFEALYILHSEEKLVDCILKDE 87

  Fly   103 ENPARPMYRYAHVFFTEVCPEELFNDLCKSCAAGKIKTLKEINIAFLPYECQVFSLDSPDTFQCL 167
            |...|  |...|:.|.::..|.|.|.|..|..|.||:|::...:.|...|.:.|.:....:...|
pombe    88 EYDKR--YPGIHIVFLDMVKEPLINKLRTSRIASKIRTVQVAYLDFTSLESRYFQVHDSFSGLRL 150

  Fly   168 YSPAFASIRSKHIERIAEQIATLCATLGEYPNVRY-------RSDWDRNIDLAASVQQKLDAYKA 225
            |.|:.|:|..:.:.::|..|.::|.:||..||:|.       .:....:..||..:.:.::.|.:
pombe   151 YHPSNAAIIRQELSKVAHGIFSVCVSLGISPNIRCYYPKNAPHASKTMSFILANQLSEIVEEYCS 215

  Fly   226 DDATMGEGPEKARSQLLILDRGFDCVSPLLHELTLQAMAYDLLPIVNDVYRY-TPGPNQPDKEV- 288
            ......|...|  |..||:||..|..:|.|||.|.|||.:|||||.|:.|.| ..||...:|..
pombe   216 KHPGYHEAASK--STCLIVDRSLDTAAPFLHEFTYQAMIHDLLPIKNEQYPYEILGPQGTEKRTG 278

  Fly   289 LLDENDDLWVELRHEHIAVVSTQVTQNLKK-------FTDSKRMGSADKSSMRDLSQMIKKMPQY 346
            .||::|.::..:||.|:.....::.::..:       |.|.:|     .:|:.|:..|:..:..:
pombe   279 KLDDDDLVYTTIRHMHMRDAIEKLMKDFNQFCIDNTLFLDKER-----ATSLNDMRSMLAGLSDF 338

  Fly   347 QKELSKYSTHLHLAEDCMKSYQ-NYVDKLCRVEQDLAMGTDAEGEKIKDHMRNIVPILLDANVSN 410
            |:...:||.||.:|::||..:: ..::.:..:||||:.|::.||:..:..:..::|:|.:.|...
pombe   339 QELRDQYSLHLTMAQECMNIFEKQQLNLIGAIEQDLSTGSNVEGKVPRSVLSELLPLLDEGNAEE 403

  Fly   411 YDKVRIIALYVMIKNGISEENLTKLFTHAQLSPKDQDMVRNLSCLGINVI---ADSRKKQYSVPR 472
            ..|:|::.||::.::||..::|.:||.|:.||...:.:.:||..||..||   .|...|:..|..
pombe   404 STKIRLLLLYIIYRDGIILQDLFRLFRHSNLSTSREQIFQNLEQLGTRVIKNLTDQSSKRKEVAN 468

  Fly   473 KERTTESTYQMSRWTPVIKDIMEDCIEDKLDLRHFPFLEGRAQNTNYH-APTSARYGH--WHKDK 534
            .....|..|::||:.|.:|.::|:.|:||||...||::......|... ..||.|...  |.:.:
pombe   469 SLPAGEDVYELSRYVPTLKVVLENLIQDKLDPELFPYVRNTTPQTEVSMEQTSLRSSRPSWTRSR 533

  Fly   535 GQAQVKNVPRLIVFIVGGVSMSEMRCAYEVTNAVRNWEVLVGSSHILSPEIFL 587
            ..|......:::||:.||.:.||:|..||:::.. |.::.:||:...||..:|
pombe   534 SMASKLPREKMLVFVAGGTTFSELRTCYELSDKY-NKDIYIGSTVCYSPNEWL 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rop	NP_001261404.1	Sec1	40..583	CDD:395791	158/565 (28%)
sec1	NP_588226.1	SEC1	1..596	CDD:227487	162/573 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	247	1.000	Domainoid score	I416
eggNOG	1	0.900	-	-		E1_COG5158
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	250	1.000	Inparanoid score	I785
OMA	1	1.010	-	-		QHG53928
OrthoFinder	1	1.000	-	-		FOG0000914
OrthoInspector	1	1.000	-	-		oto101401
orthoMCL	1	0.900	-	-		OOG6_100816
Panther	1	1.100	-	-	LDO	PTHR11679
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2284
SonicParanoid	1	1.000	-	-		X527
TreeFam	1	0.960	-	-
	13	12.860