Protein Alignment Rop and sec1

DIOPT Version :10

• Sequence 1: NP_523916.2
• Gene: Rop / 38493
• FlyBaseID: FBgn0004574
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_588226.1
• Gene: sec1 / 2538850
• PomBaseID: SPCC584.05
• Length: 693
• Species: Schizosaccharomyces pombe
• Alignment Length: 573
• Identity: 162/573 - (28%)
• Similarity: 293/573 - (51%)
• Gaps: 33/573 - (5%)

  Fly    38 EWRVLVVDKLGMRMVSACTKMHEISAEGITLVEDINKKREPLPTMDAIYLITPSDESVRGLIRDF 102
            :|:||:||.....:::....:|.:..|.|..||.:...|.|..:.:|:|::...::.|..:::|.
pombe    23 KWKVLIVDTKTADIINHFITIHSLLEEKIAAVEILENPRTPNSSFEALYILHSEEKLVDCILKDE 87

  Fly   103 ENPARPMYRYAHVFFTEVCPEELFNDLCKSCAAGKIKTLKEINIAFLPYECQVFSLDSPDTFQCL 167
            |...|  |...|:.|.::..|.|.|.|..|..|.||:|::...:.|...|.:.|.:....:...|
pombe    88 EYDKR--YPGIHIVFLDMVKEPLINKLRTSRIASKIRTVQVAYLDFTSLESRYFQVHDSFSGLRL 150

  Fly   168 YSPAFASIRSKHIERIAEQIATLCATLGEYPNVRY-------RSDWDRNIDLAASVQQKLDAYKA 225
            |.|:.|:|..:.:.::|..|.::|.:||..||:|.       .:....:..||..:.:.::.|.:
pombe   151 YHPSNAAIIRQELSKVAHGIFSVCVSLGISPNIRCYYPKNAPHASKTMSFILANQLSEIVEEYCS 215

  Fly   226 DDATMGEGPEKARSQLLILDRGFDCVSPLLHELTLQAMAYDLLPIVNDVYRY-TPGPNQPDKEV- 288
            ......|...|  |..||:||..|..:|.|||.|.|||.:|||||.|:.|.| ..||...:|..
pombe   216 KHPGYHEAASK--STCLIVDRSLDTAAPFLHEFTYQAMIHDLLPIKNEQYPYEILGPQGTEKRTG 278

  Fly   289 LLDENDDLWVELRHEHIAVVSTQVTQNLKK-------FTDSKRMGSADKSSMRDLSQMIKKMPQY 346
            .||::|.::..:||.|:.....::.::..:       |.|.:|     .:|:.|:..|:..:..:
pombe   279 KLDDDDLVYTTIRHMHMRDAIEKLMKDFNQFCIDNTLFLDKER-----ATSLNDMRSMLAGLSDF 338

  Fly   347 QKELSKYSTHLHLAEDCMKSYQ-NYVDKLCRVEQDLAMGTDAEGEKIKDHMRNIVPILLDANVSN 410
            |:...:||.||.:|::||..:: ..::.:..:||||:.|::.||:..:..:..::|:|.:.|...
pombe   339 QELRDQYSLHLTMAQECMNIFEKQQLNLIGAIEQDLSTGSNVEGKVPRSVLSELLPLLDEGNAEE 403

  Fly   411 YDKVRIIALYVMIKNGISEENLTKLFTHAQLSPKDQDMVRNLSCLGINVI---ADSRKKQYSVPR 472
            ..|:|::.||::.::||..::|.:||.|:.||...:.:.:||..||..||   .|...|:..|..
pombe   404 STKIRLLLLYIIYRDGIILQDLFRLFRHSNLSTSREQIFQNLEQLGTRVIKNLTDQSSKRKEVAN 468

  Fly   473 KERTTESTYQMSRWTPVIKDIMEDCIEDKLDLRHFPFLEGRAQNTNYH-APTSARYGH--WHKDK 534
            .....|..|::||:.|.:|.::|:.|:||||...||::......|... ..||.|...  |.:.:
pombe   469 SLPAGEDVYELSRYVPTLKVVLENLIQDKLDPELFPYVRNTTPQTEVSMEQTSLRSSRPSWTRSR 533

  Fly   535 GQAQVKNVPRLIVFIVGGVSMSEMRCAYEVTNAVRNWEVLVGSSHILSPEIFL 587
            ..|......:::||:.||.:.||:|..||:::.. |.::.:||:...||..:|
pombe   534 SMASKLPREKMLVFVAGGTTFSELRTCYELSDKY-NKDIYIGSTVCYSPNEWL 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rop	NP_523916.2	Sec1	40..589	CDD:460020	161/571 (28%)
sec1	NP_588226.1	SEC1	1..596	CDD:227487	162/573 (28%)