Protein Alignment Rop and sly-1

DIOPT Version :9

• Sequence 1: NP_001261404.1
• Gene: Rop / 38493
• FlyBaseID: FBgn0004574
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_499317.2
• Gene: sly-1 / 185707
• WormBaseID: WBGene00009654
• Length: 675
• Species: Caenorhabditis elegans
• Alignment Length: 705
• Identity: 149/705 - (21%)
• Similarity: 277/705 - (39%)
• Gaps: 176/705 - (24%)

  Fly     1 MALKVLVGQKLMNEVVKYKPPPPKKQGVTSAAGAGGMEWRVLVVDKLGMRMVSACTKMHEISAEG 65
            :||:.::.   :||       |....||....      |:|||:|:.|..::|....:.::...|
 Worm    14 VALRTMIN---LNE-------PVVNSGVREPV------WKVLVLDRTGQDIISPLLPVKQLRELG 62

  Fly    66 ITLVEDINKKREPLPTMDAIYLITPSDESVRGLIRDFENPARPMYRYAHVFFTEVCP------EE 124
            :||...|..:||||..:.|:|.::|:||::..:..|.:   :.||...:..|  :.|      |.
 Worm    63 VTLHLLIGARREPLTDVPAVYFVSPNDENIDLMSEDLK---KAMYDSFYCNF--ISPLARPRLES 122

  Fly   125 LFNDLCKSCAAGKIKTLKEINIAFLPYECQVFSL-----DSPDTFQCLYSPAFASIR-SKHIERI 183
            |.:......|..:::.:.:..:.|:..|..:|.|     :|..::..:.||..:.:. :..::.|
 Worm   123 LASAAVHGGAVSQVQKVVDQYLNFISLEDDLFVLRRYSENSTFSYHAMNSPGTSDVAVNAMLDSI 187

  Fly   184 AEQIATLCATLGEYPNVRYRSDWDRNIDLAASVQQKLD-------------AYKADDATMGEGPE 235
            |:.:..:|||:|..|.:|....     :.|..|.:|||             .:..|...||. .:
 Worm   188 ADGLFAVCATMGIVPIIRCPKG-----NAAEMVAKKLDQKLRDNLRDSRNNLFTMDGVRMGL-LQ 246

  Fly   236 KARSQLLILDRGFDCVSPLLHELTLQAMAYDLLPIVNDVYRYTPGPN----QPDKEVLLDENDDL 296
            .:|..|:|.||..|..:.|.|..|.||:.:|:|.:  |..|.|...:    :.|.::....:|.|
 Worm   247 TSRPLLVIGDRSADLATMLHHTWTYQALMHDVLEL--DQNRVTISTSSTGKKKDYDMATGGSDKL 309

  Fly   297 WVELRHEHIAVVSTQVTQNL----KKFTDSKR----MGSADKSSMRD-------------LSQMI 340
            |...:......|:..|.:||    .|..|.|:    :|.:.:|...|             |...:
 Worm   310 WNNHKGSAFPTVAEAVQENLDDYRSKEDDIKKIKQALGLSGESEAADEALTNVLADTTAKLGSTV 374

  Fly   341 KKMPQYQKELSKYSTHLHLAE---DCMKSYQNYVDKLCRVEQDLAMGTDAEGEKIK-----DHMR 397
            ..:|...:.......|.::|.   |.:|  :..:|.|..:||.|...:..:....:     :|..
 Worm   375 MSLPDLLESKRLIDLHTNIATTLLDVIK--ERKLDVLFELEQKLLQHSPLDQPVTQFLSNINHQE 437

  Fly   398 NIVPILLDA-------NVSNYDKVRIIALYVMIKNGISE---ENLTKLFTHAQLSPKDQDM---- 448
            :::.:|:.|       |.:.||::    :.::.:.||.|   :::.||.:.:||..:..:.
 Worm   438 DVLRVLIIAFLCQETVNQNGYDQM----MNLLRERGIEESALKHVQKLKSISQLGSRAANSAHTE 498

  Fly   449 ------VRNLSCLGINVIADSRK-----------KQYSVPRKE-----RTTEST---------YQ 482
                  .:.:|..| .:::.|.|           |::::|..:     .|..|:         .|
 Worm   499 EHQGAGTKTISMFG-KLLSHSSKFVMEGVKNLVPKEHNLPLTKMIDSLNTPPSSTGISSAVGINQ 562

  Fly   483 M---SRWTPVIKDIMEDCIEDKLDLRHFPFLEGRAQNTNYHAPTS-----ARYGHWHKDKGQAQV 539
            |   |...|.|.||.  |..|       |.|        .|.||.     ||         |...
 Worm   563 MIGGSSQGPDIDDIY--CFFD-------PKL--------MHQPTKETILLAR---------QQSA 601

  Fly   540 KNVPRLIVFIVGGVSMSEMRCAYEVTNAVRNWEVLVGSSHILSPEIFLSDLGSLS 594
            ::|   |:|:|||.:..|.:...:.........|..|.:.:::|..|...:...|
 Worm   602 QDV---ILFVVGGGNYVEYQNLVDYGKRKNLMRVTYGCTELVNPAQFCDQVSCCS 653

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rop	NP_001261404.1	Sec1	40..583	CDD:395791	138/653 (21%)
sly-1	NP_499317.2	Sec1	7..650	CDD:301618	148/700 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910