Protein Alignment Rop and vps-33.2

DIOPT Version :9

• Sequence 1: NP_001261404.1
• Gene: Rop / 38493
• FlyBaseID: FBgn0004574
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_495342.2
• Gene: vps-33.2 / 174095
• WormBaseID: WBGene00016960
• Length: 617
• Species: Caenorhabditis elegans
• Alignment Length: 632
• Identity: 121/632 - (19%)
• Similarity: 230/632 - (36%)
• Gaps: 151/632 - (23%)

  Fly    42 LVVDKLGMRMVSACTKMHEISAEGITLVEDINKKREP----LPTMDAIYLITPSDESVRGLIRDF 102
            |.:||..:|.:.......::...|:..:...:.::.|    :.....::.:.|:.|:.|.::...
 Worm    38 LFIDKCLLRPLDMIATSSDMKRHGVKRIMHFDLQKSPQVWNIEIDQRVFFLRPNVENARKIVEYV 102

  Fly   103 ENPARPMYRYAHVFFTEVCPEELFN-DLC--KSCAAGKIKTLKEINIAFLPYECQVFSLD----- 159
            |..:.  .|...|.:   |..:|.. ||.  .|...|.|..| .:|:..||.|..:|||.
 Worm   103 EESSE--NRSICVIW---CNRQLEECDLAFESSGVIGHITQL-SLNMCLLPLESDLFSLQHVESA 161

  Fly   160 SPDTFQCLYSPAFASIRSKHIERIAEQIATLCATLGEYPNV-----RYRSDWDRNIDLAASVQQK 219
            .||.|.                 :|.....|....|..|.|     ..::.|  |:..|.....:
 Worm   162 QPDLFS-----------------VANMFVALQNLYGVIPTVYGLGSESKNLW--NLVHALCSSNE 207

  Fly   220 LDAYKADDATMGEGPEKARSQLLILDRGFDCV---------SPLLHE-LTLQ----AMAYDLL-- 268
            |.|          .|::..|.|.:.||..|.|         ..|||| .|:.    |...||.
 Worm   208 LRA----------RPDQPISHLFLFDRQLDPVPVLLTGASYEGLLHEFFTIDCGKLAFPVDLRKQ 262

  Fly   269 ----PIVNDVYRYTPGPNQPDKE---------VLLDENDDLWVELRHEHIAVVSTQVTQNLKKFT 320
                |:..|.....|   :.|||         |.||..:|::..:|::|:...        .:|.
 Worm   263 VQTGPLDFDWIEINP---EEDKEAHQQNRGDTVKLDNCEDIFASIRNKHVTAA--------LEFL 316

  Fly   321 DSKRMG---SADKSSM----RDLSQMIKK-MPQYQKELSKYSTHLHLAEDCMK--SYQNYVDKLC 375
            .||...   |.:||||    .|....::| :...:|:......|::..|..|.  ..::| ..:.
 Worm   317 HSKAKSIQKSIEKSSMIDDVADYRNFVEKDLRALKKDHKHCELHINACEMMMNKVKMEDY-RTMF 380

  Fly   376 RVEQDLAMGTDAEGEKIKDHMRNIVPILLDANVSNYDKVRIIALYVMIKNGISEENLTKLFTHAQ 440
            ::|.::.:|| ...|:..|.:...||:....:|    .:.:::|..:..:|:.::...: |....
 Worm   381 KLEHEMLLGT-VTHEEYFDFVFERVPMRSCRDV----VLSMMSLASLKLDGVPDDTYNE-FVEMY 439

  Fly   441 LSPKDQDMVRNLSCLGIN-------------VIADSRKKQYSVPRKERTTESTYQM--------- 483
            |.....:.:..|..|..:             .|::..:...::.||.|..:....|
 Worm   440 LQKYGYEHMFELQNLRNSRVIYARRHIAHDRTISERARTWETLARKFRIVKGNEPMDMSNPSDMS 504

  Fly   484 ----SRWTPVIKDIMEDCIEDKLDLRHFPFLEGR----AQNTNYHAPTSARYGHWHKDKGQAQVK 540
                :|.:|::..|:||.|:...:...:..:.|:    .:...|.|..........|
 Worm   505 YVFGARISPLLCKIVEDTIDHGWNQAEYERIIGKDKVLVEENTYIAADRRPDNRTRK-------- 561

  Fly   541 NVPRLIVFIVGGVSMSEMRCAYEVTNAVRNWEVLVGSSHILSPEIFL 587
               .::||:.||::..|: .|..:....:|:.:|:.::|::....:|
 Worm   562 ---AIMVFVNGGITYWEV-AALRLLAIQKNFRILICTTHVIKKREYL 604

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rop	NP_001261404.1	Sec1	40..583	CDD:395791	120/626 (19%)
vps-33.2	NP_495342.2	Sec1	36..598	CDD:307231	120/624 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810