Protein Alignment Rop and Rop

DIOPT Version :10

• Sequence 1: NP_523916.2
• Gene: Rop / 38493
• FlyBaseID: FBgn0004574
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: XP_061497785.1
• Gene: Rop / 1272929
• VectorBaseID: AGAMI1_011998
• Length: 589
• Species: Anopheles gambiae
• Alignment Length: 599
• Identity: 470/599 - (78%)
• Similarity: 525/599 - (87%)
• Gaps: 13/599 - (2%)

  Fly     1 MALKVLVGQKLMNEVVKYKPPPPKKQGVTSAAGAGGMEWRVLVVDKLGMRMVSACTKMHEISAEG 65
            ||||:|||||:|||||:.|         |.:.|..|.|||:|:||||.|||||||||||||||||
Mosquito     1 MALKLLVGQKIMNEVVRSK---------TKSDGKPGTEWRILIVDKLAMRMVSACTKMHEISAEG 56

  Fly    66 ITLVEDINKKREPLPTMDAIYLITPSDESVRGLIRDFENPARPMYRYAHVFFTEVCPEELFNDLC 130
            :||||||||||||||.::|:||||||::|:|.|:|||||||:|.|:.||||||||||||||||:|
Mosquito    57 VTLVEDINKKREPLPAIEAVYLITPSEDSIRLLMRDFENPAKPTYKAAHVFFTEVCPEELFNDIC 121

  Fly   131 KSCAAGKIKTLKEINIAFLPYECQVFSLDSPDTFQCLYSPAFASIRSKHIERIAEQIATLCATLG 195
            ||..:.||||||||||||||||.||:|||||.||||.||||.||.||.::|||||||||||||||
Mosquito   122 KSVVSRKIKTLKEINIAFLPYESQVYSLDSPVTFQCAYSPALASARSGNMERIAEQIATLCATLG 186

  Fly   196 EYPNVRYRSDWDRNIDLAASVQQKLDAYKADDATMGEGPEKARSQLLILDRGFDCVSPLLHELTL 260
            |||:|||||:||.|::||..|||||||||||:.||||||||||||||||||||||||||||||||
Mosquito   187 EYPSVRYRSEWDGNVELAQMVQQKLDAYKADEPTMGEGPEKARSQLLILDRGFDCVSPLLHELTL 251

  Fly   261 QAMAYDLLPIVNDVYRYTPGPNQPDKEVLLDENDDLWVELRHEHIAVVSTQVTQNLKKFTDSKRM 325
            |||||||||||||||::.|.||..:|||||||||||||:|||:||||||..|||.||.||:|||:
Mosquito   252 QAMAYDLLPIVNDVYKFIPSPNAAEKEVLLDENDDLWVDLRHQHIAVVSQSVTQYLKSFTESKRL 316

  Fly   326 GSADKSSMRDLSQMIKKMPQYQKELSKYSTHLHLAEDCMKSYQNYVDKLCRVEQDLAMGTDAEGE 390
            ..::|.||:||||||||||||||:|||||||||||||||||||.|||||||||||||||||||||
Mosquito   317 TQSEKQSMKDLSQMIKKMPQYQKQLSKYSTHLHLAEDCMKSYQGYVDKLCRVEQDLAMGTDAEGE 381

  Fly   391 KIKDHMRNIVPILLDANVSNYDKVRIIALYVMIKNGISEENLTKLFTHAQLSPKDQDMVRNLSCL 455
            |||||||||||||||.|||||||||||||||||||||||||||||.||||:..|:::|:.||..|
Mosquito   382 KIKDHMRNIVPILLDQNVSNYDKVRIIALYVMIKNGISEENLTKLVTHAQIDQKEREMIHNLIHL 446

  Fly   456 GINVIAD-SRKKQYSVPRKERTTESTYQMSRWTPVIKDIMEDCIEDKLDLRHFPFLEGRAQNTNY 519
            ||||||| :|||.|:||||||..|.|||||||||||||||||.|::|||.||||||.|| :...:
Mosquito   447 GINVIADGNRKKSYTVPRKERINEHTYQMSRWTPVIKDIMEDAIDNKLDERHFPFLGGR-KMAGF 510

  Fly   520 HAPT--SARYGHWHKDKGQAQVKNVPRLIVFIVGGVSMSEMRCAYEVTNAVRNWEVLVGSSHILS 582
            ||||  |||||||||||.|..||||||||:|:|||.|.||:|||||||.||:||||.:||||||:
Mosquito   511 HAPTSSSARYGHWHKDKSQTAVKNVPRLIMFVVGGCSYSEIRCAYEVTAAVKNWEVYIGSSHILT 575

  Fly   583 PEIFLSDLGSLSKE 596
            ||.||||||||:||
Mosquito   576 PETFLSDLGSLNKE 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rop	NP_523916.2	Sec1	40..589	CDD:460020	442/551 (80%)
Rop	XP_061497785.1	None