Protein Alignment RfC4 and CHTF18

DIOPT Version :10

• Sequence 1: NP_523915.1
• Gene: RfC4 / 38492
• FlyBaseID: FBgn0260985
• Length: 331
• Species: Drosophila melanogaster
• Sequence 2: XP_005255528.1
• Gene: CHTF18 / 63922
• HGNCID: 18435
• Length: 1003
• Species: Homo sapiens
• Alignment Length: 297
• Identity: 62/297 - (20%)
• Similarity: 106/297 - (35%)
• Gaps: 86/297 - (28%)

  Fly     2 PEEPEKTADDKRSHLPWIEKYRPVKFKEIVGNEDT------------------------------ 36
            |||......|..||..|::::.|..:.|::.::.|
Human   294 PEEEPTDGQDASSHCLWVDEFAPRHYTELLSDDFTNRCLLKWLKLWDLVVFGHERPSRKPRPSVE 358

  Fly    37 VARLSVFAT-----------------QGNAPN-------IIIAGPPGVGKTTTIQCLARILLGDS 77
            .||:|..||                 .|..|:       .::.||||:||||....:||   ...
Human   359 PARVSKEATAPGKWKSHEQVLEEMLEAGLDPSQRPKQKVALLCGPPGLGKTTLAHVIAR---HAG 420

  Fly    78 YKEAVLELNASNERGIDVVRNKIKMFAQQKVTL-PRGRHKIVILDEADSMTEGAQQAL------- 134
            |  :|:|:|||::|..:|.|.:|:...|.:..| ..|:...:::||.|.....|...|
Human   421 Y--SVVEMNASDDRSPEVFRTRIEAATQMESVLGAGGKPNCLVIDEIDGAPVAAINVLLSILNRK 483

  Fly   135 ------------------RRTMEIYSSTTRFALACNTS-EKIIEPIQSRCAMLRFTKLSDAQVLA 180
                              ||..|...........||.. ...:..::.:..:|.|.....::::.
Human   484 GPQEVGPQGPAVPSGGGRRRRAEGGLLMRPIICICNDQFAPSLRQLKQQAFLLHFPPTLPSRLVQ 548

  Fly   181 KLIEVAKWEKLNYTEDGLEAIVFTAQGDMRQGLNNLQ 217
            :|.||:..:.:......|.|:......|:|..:|.||
Human   549 RLQEVSLRQGMRADPGVLAALCEKTDNDIRACINTLQ 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RfC4	NP_523915.1	PLN03025	16..330	CDD:178596	56/283 (20%)
CHTF18	XP_005255528.1	PRK04195	394..>622	CDD:235250	45/197 (23%)