Protein Alignment RfC4 and RFC3

DIOPT Version :10

• Sequence 1: NP_523915.1
• Gene: RfC4 / 38492
• FlyBaseID: FBgn0260985
• Length: 331
• Species: Drosophila melanogaster
• Sequence 2: NP_002906.1
• Gene: RFC3 / 5983
• HGNCID: 9971
• Length: 356
• Species: Homo sapiens
• Alignment Length: 300
• Identity: 85/300 - (28%)
• Similarity: 127/300 - (42%)
• Gaps: 67/300 - (22%)

  Fly    18 WIEKYRPVKFKEIVGNEDTVARLSVFATQGNAPNIIIAGPPGVGKTTTIQCLARILLG------- 75
            |::||||.....:..:::..|:|......|:.|::::.||.|.||.|.|.|:.|.|.|
Human     4 WVDKYRPCSLGRLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELYGVGVEKLR 68

  Fly    76 --------DSYKEAV---------LELNASNERGID--VVRNKIKMFA--QQKVTLPRGRHKIVI 119
                    .|.|:..         ||:|.|:....|  |::..:|..|  ||..|..:...|:|:
Human    69 IEHQTITTPSKKKIEISTIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQLETNSQRDFKVVL 133

  Fly   120 LDEADSMTEGAQQALRRTMEIYSSTTRFALACNTSEKIIEPIQSRCAMLRFTKLSDAQVLAKLIE 184
            |.|.|.:|:.||.|||||||.|.||.|..|.||::.|:|.||:|||..:|....|...:...|..
Human   134 LTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRCLAVRVPAPSIEDICHVLST 198

  Fly   185 VAKWEKLNYTED-----------------------GLEAIVFTAQGD---------MRQGLNNL- 216
            |.|.|.||....                       .::...|||..:         :|:..|.:
Human   199 VCKKEGLNLPSQLAHRLAEKSCRNLRKALLMCEACRVQQYPFTADQEIPETDWEVYLRETANAIV 263

  Fly   217 -QSTAQGFGDITAE--NVFKVCDEPH---PKLLEEMIHHC 250
             |.|.|...::...  .:...|..|.   ..||.|::|:|
Human   264 SQQTPQRLLEVRGRLYELLTHCIPPEIIMKGLLSELLHNC 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RfC4	NP_523915.1	PLN03025	16..330	CDD:178596	84/299 (28%)
RFC3	NP_002906.1	PRK12402	3..339	CDD:237090	84/299 (28%)