DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RfC4 and CG8142

DIOPT Version :9

Sequence 1:	NP_523915.1	Gene:	RfC4 / 38492	FlyBaseID:	FBgn0260985	Length:	331	Species:	Drosophila melanogaster
Sequence 2:	NP_573245.1	Gene:	CG8142 / 32763	FlyBaseID:	FBgn0030871	Length:	353	Species:	Drosophila melanogaster

Alignment Length:	293	Identity:	115/293 - (39%)
Similarity:	161/293 - (54%)	Gaps:	38/293 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 PWIEKYRPVKFKEIVGNEDTVARLSVFATQGNAPNIIIAGPPGVGKTTTIQCLARILLGDSYKEA 81
            ||:|||||....::|...:.||.|......|:.||:::.||||.|||:||...:|.:.||.:|:.
  Fly    31 PWVEKYRPRNVDDVVEQSEVVAVLRKCVEGGDLPNMLLYGPPGTGKTSTILAASRQIFGDMFKDR 95

  Fly    82 VLELNASNERGIDVVRNKIKMFAQQKVT--LPRGR----HKIVILDEADSMTEGAQQALRRTMEI 140
            :||||||:||||:|||.|||.|:|...:  .|.|:    .||:|||||||||..||.|||||||.
  Fly    96 ILELNASDERGINVVRTKIKNFSQLSASSVRPDGKPCPPFKIIILDEADSMTHAAQSALRRTMEK 160

  Fly   141 YSSTTRFALACNTSEKIIEPIQSRCAMLRFTKLSDAQVLAKLIEVAKWEKLNYTEDGLEAIVFTA 205
            .|.:|||.|.||...:||.||.|||:..||..|.:.:|:.:|..:.:.|.:...:|..::||..:
  Fly   161 ESRSTRFCLICNYVSRIIVPITSRCSKFRFKALGEDKVIDRLKYICEMEGVKIEDDAYKSIVKIS 225

  Fly   206 QGDMRQGLNNLQSTAQGFGDITAENVFKVCDEPHPKLLEEMIHHCAANDIHKAYKILAKLWKLGY 270
            .||:|:.:..|||..:..|   .|::....|      |.||                     .|.
  Fly   226 GGDLRRAITTLQSCYRLKG---PEHIINTAD------LFEM---------------------SGV 260

  Fly   271 SPEDIIANIFRVCKRINIDEHLKLDFIREIGIT 303
            .||..:.:...||:..|. |.|: .|:||||.:
  Fly   261 IPEYYLEDYLEVCRSGNY-ERLE-QFVREIGFS 291

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RfC4	NP_523915.1	PLN03025	16..330	CDD:178596	115/293 (39%)
		AAA	31..165	CDD:99707	72/139 (52%)
		Rep_fac_C	254..322	CDD:285713	13/50 (26%)
CG8142	NP_573245.1	rfc	31..344	CDD:234763	115/293 (39%)
		AAA	45..187	CDD:99707	74/141 (52%)
		AAA_assoc_2	211..>256	CDD:292811	13/53 (25%)
		Rep_fac_C	<293..344	CDD:285713
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45455787
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0470
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	55	1.000	Inparanoid score	I449
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1071197at2759
OrthoFinder	1	1.000	-	-		FOG0000505
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11669
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.900