Protein Alignment RfC4 and Rad17

DIOPT Version :10

• Sequence 1: NP_523915.1
• Gene: RfC4 / 38492
• FlyBaseID: FBgn0260985
• Length: 331
• Species: Drosophila melanogaster
• Sequence 2: NP_035363.2
• Gene: Rad17 / 19356
• MGIID: 1333807
• Length: 688
• Species: Mus musculus
• Alignment Length: 276
• Identity: 68/276 - (24%)
• Similarity: 124/276 - (44%)
• Gaps: 70/276 - (25%)

  Fly     6 EKTADDKRSHLPWIEKYRPVKFKEIVGNEDTVAR---------LSVFATQGNAPNIIIAGPPGVG 61
            |:.:|::    ||::||:|....|:..::..:..         |.|...||.:. ::|.||||.|
Mouse    82 ERLSDNE----PWVDKYKPETQHELAVHKKKIEEVETWLKAQVLEVKPKQGGSV-LLITGPPGCG 141

  Fly    62 KTTTIQCLARIL---------------LGDSYKEAV-LELNAS-----------NERGIDVVR-N 98
            |||||:.|::.|               ..|.|||.: ||.|.|           |:..:...: :
Mouse   142 KTTTIKILSKELGIQVQEWVNPILPDFQKDDYKELLSLESNFSVVPYQSQIAVFNDFLLRATKYS 206

  Fly    99 KIKMFAQQKVTLPRGRHKIVILDEADSM----TEGAQQALRRTMEIYSSTTRFALACNTS----E 155
            |::|......|    ..||::::|..:.    .....:.||:.::|......|.::.:.|    :
Mouse   207 KLQMLGDDLTT----DKKIILVEELPNQFYRDPNALHEILRKHVQIGRCPLVFIVSDSVSGDNNQ 267

  Fly   156 KIIEP--IQSRCAM--LRFTKLSDAQVLAKL-----IEVAK-WEKL---NYTEDGLEAIVFTAQG 207
            :::.|  ||..|::  :.|..::...::..|     ||.:| .||:   |.|  .||.:.....|
Mouse   268 RLLFPRNIQEECSVSNISFNPVAPTIMMKFLNRIVTIEASKNGEKIIVPNKT--SLELLCQGCSG 330

  Fly   208 DMRQGLNNLQ-STAQG 222
            |:|..:|:|| |:::|
Mouse   331 DIRSAINSLQFSSSKG 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RfC4	NP_523915.1	PLN03025	16..330	CDD:178596	66/266 (25%)
Rad17	NP_035363.2	rad24	13..653	CDD:129690	68/276 (25%)
		RAD1-binding motif. /evidence=ECO:0000250|UniProtKB:O75943	17..25
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..84		1/1 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	342..379		2/5 (40%)
		Interaction with MCM7. /evidence=ECO:0000250|UniProtKB:O75943	431..688
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	605..688