Protein Alignment ens and MAP7

DIOPT Version :9

• Sequence 1: NP_001097498.1
• Gene: ens / 38491
• FlyBaseID: FBgn0264693
• Length: 1241
• Species: Drosophila melanogaster
• Sequence 2: NP_001185538.1
• Gene: MAP7 / 9053
• HGNCID: 6869
• Length: 779
• Species: Homo sapiens
• Alignment Length: 1189
• Identity: 256/1189 - (21%)
• Similarity: 383/1189 - (32%)
• Gaps: 496/1189 - (41%)

  Fly     7 QHGNISTNPEVENTAKRPESREGSAERKAHAFAPAKISGCSAGATLHWFAQVGGQISASEDDSQA 71
            ::|| |..|      |.|:|.:...::.|.:...:.|||            .....|.::.|...
Human    36 KNGN-SRRP------KAPDSYKVQDKKNASSRPASAISG------------QNNNHSGNKPDPPP 81

  Fly    72 SKDREEKLKYARDRQNEERH-----RKIEELRAQAEAAQRYREQKEEERRRRIEEIRTRDTEKRH 131
            ....:::.:.||:|: |||.     |:|..|..:..|.|.| |:..|||::|:||.|.::..:|.
Human    82 VLRVDDRQRLARERR-EEREKQLAAREIVWLEREERARQHY-EKHLEERKKRLEEQRQKEERRRA 144

  Fly   132 QVEERKKAIFEAEKERREYILKKNQERESRIEVKKRDRNSIGFAFGSSTPRLLDVPADYGLVSPS 196
            .|||:::...|.:|||.|.::::..||..:.: :|.:|.|.|.:...| |.:.....|
Human   145 AVEEKRRQRLEEDKERHEAVVRRTMERSQKPK-QKHNRWSWGGSLHGS-PSIHSADPD------- 200

  Fly   197 AFWGQRRSTSISNVAGASLTRRSSERELADSGAKKRASSST----DRQDDHRRKSSSMYEVFNWG 257
                 |||.|..|::           :..|....||.|||:    :..|..||...|.:|
Human   201 -----RRSVSTMNLS-----------KYVDPVISKRLSSSSATLLNSPDRARRLQLSPWE----- 244

  Fly   258 YSNDEPPKRFSLSIAGSEINIDGPANPHPPPTSKQTANAHRPTNLTTTT----ATSTTTAGHNNF 318
                           .|.:|                       .|.|.|    |.|.:||..:.
Human   245 ---------------SSVVN-----------------------RLLTPTHSFLARSKSTAALSG- 270

  Fly   319 NNNNSYRKEDSVDSSPMVFRSVYRRKTDLMPTIPSPRDGHYGSRGSLSSTPARTPGR-AYSMNRL 382
                                      ..::|..|.          |.|.:|...|.: |:|.|.:
Human   271 --------------------------EAVIPICPR----------SASCSPIIMPYKAAHSRNSM 299

  Fly   383 DQ----LAQPIRRNGEHMRAILE-----RERRERELEMLDETASLGGGGGRRGAGSSARARRAGS 438
            |:    :..|   .|...|.|:.     ::.||||     ....|..|..|..:.|:.:||:.
Human   300 DRPKLFVTPP---EGSSRRRIIHGTASYKKERERE-----NVLFLTSGTRRAVSPSNPKARQP-- 354

  Fly   439 AGSGSSSAAGIMSRSMTHLAGGGGQRERGKYSLGGGISTSFRPLASGAGGQRDSTSKSMTQISSW 503
                :.|...:.|:|:.||.|
Human   355 ----ARSRLWLPSKSLPHLPG-------------------------------------------- 371

  Fly   504 SVYGSTAPQQPPPNHLHHLRQSTLGLQTAATKKYLQSSFASASSFNSASFRANATGRGRQQQYAI 568
                                                                             
Human   372 ----------------------------------------------------------------- 371

  Fly   569 STNPHRFLDLDPNSLLLMNSASLLVNAGSRSGNATPGGHFNNSRPGSAMSTSTNMSTSGLVPRRP 633
                                              ||       ||           ||.|.|...
Human   372 ----------------------------------TP-------RP-----------TSSLPPGSV 384

  Fly   634 ATAPRKPRPASIAGTGMSLEEINKLKRDQKPPVKTTAASPSAQTTPKRTANLMSTSLIVTSSSSR 698
            ..||.:.||.|..       .|..:||:    ||........:..|::.||..|     ....:.
Human   385 KAAPAQVRPPSPG-------NIRPVKRE----VKVEPEKKDPEKEPQKVANEPS-----LKGRAP 433

  Fly   699 LSSAEKKTPSKREPPVPKAASASKALPSRTASSERISRLTKEPKTKDTSAMTRSMIVTSSSTSTI 763
            |...|:.|..:|.|..|:...|:
Human   434 LVKVEEATVEERTPAEPEVGPAA------------------------------------------ 456

  Fly   764 TKPAPAPVAPTSAPVPEQNGVAKEVEKTTADEPVPEAEVPTEAPVVVPSVSKAEKEALNTEKTEE 828
              ||.|| ||.|||.|             |..|.| |.|||.|.|..||
Human   457 --PAMAP-APASAPAP-------------ASAPAP-APVPTPAMVSAPS---------------- 488

  Fly   829 GARQEEEQILAVESVPEALVTSINVEEKSDEGNEKEVPKPQEQAAPKKPSRSKENSEVRELTPPE 893
                                :::|.
Human   489 --------------------STVNA---------------------------------------- 493

  Fly   894 GADLMTASMMAKKITTE-EEAKAALAERRRLAREEAERQAELERQRLEAERLAEIKAQEEEAERQ 957
                 :||:.....||: |||...|||:||||||:.|::   ||:|.|.|   |::.|:.|...|
Human   494 -----SASVKTSAGTTDPEEATRLLAEKRRLAREQREKE---ERERREQE---ELERQKREELAQ 547

  Fly   958 RLFEEESTRLAEEQRRGEEERLRKAIEEAQQREEEEKRRREEEEKQRVERE-EAEKKAKEEAEKQ 1021
            |:.||.:||..||.||.|.|:.|:. ||..||:.||:..||.||.:|.:|: |.|.:.:||||:.
Human   548 RVAEERTTRREEESRRLEAEQAREK-EEQLQRQAEERALREREEAERAQRQKEEEARVREEAERV 611

  Fly  1022 RVEVAERLKREEKEREERRKRVEAIMLRTRKGGAATTPSKDA--NDKAAPAATAPENNSSSNSSV 1084
            |.|..:..:|||:||.||:||:|.||.|||:..|....:.|.  .|.|..|.|.....|:...:.
Human   612 RQEREKHFQREEQERLERKKRLEEIMKRTRRTEATDKKTSDQRNGDIAKGALTGGTEVSALPCTT 676

  Fly  1085 TGSSNNSAEGSPSAADSTPAPTATET---VQEAPNSQAMYEQSVLDKE--NSLINSFSTMIIDEN 1144
            ....|....|||....|..:....|:   :::.||...:..|:...:|  |..|.|..:.:...|
Human   677 NAPGNGKPVGSPHVVTSHQSKVTVESTPDLEKQPNENGVSVQNENFEEIINLPIGSKPSRLDVTN 741

  Fly  1145 AKNLQQVSNGKLLVDFEST 1163
            :::.:...|..|..|.|.|
Human   742 SESPEIPLNPILAFDDEGT 760

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ens	NP_001097498.1	MAP7	920..1060	CDD:283355	64/140 (46%)
MAP7	NP_001185538.1	PTZ00108	<101..317	CDD:240271	70/324 (22%)
		MAP7	125..>181	CDD:398996	19/56 (34%)
		MAP7	491..649	CDD:398996	75/209 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165143732
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR15073
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	3	2.990