DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ens and Map7d1

DIOPT Version :9

Sequence 1:	NP_001097498.1	Gene:	ens / 38491	FlyBaseID:	FBgn0264693	Length:	1241	Species:	Drosophila melanogaster
Sequence 2:	XP_006238963.1	Gene:	Map7d1 / 681287	RGDID:	1597986	Length:	849	Species:	Rattus norvegicus

Alignment Length:	986	Identity:	238/986 - (24%)
Similarity:	359/986 - (36%)	Gaps:	297/986 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   279 DGPANPHPPPTSKQT-------------ANAHRPTNLTTTTATSTTTAGHNNFNNNNSYRKEDSV 330
            :|..:|.||||....             .||..|..|.....:.|         ...|.:.....
  Rat    30 EGDPSPPPPPTPMSALVPDTPPDTPPAMKNASTPQQLPLEPVSPT---------GQVSPQPAPPP 85

  Fly   331 DSSPMVFRSVYRRKTDLMPTIPSPRDGHYGSRGSLSSTPARTPGRAYSMNRLDQLAQPIRRNGEH 395
            |..|    |...:.....||...|||.....|   ||.|:.|   |...:......|.:::.||
  Rat    86 DECP----SSEAKSRGPTPTATGPRDAKPSQR---SSQPSPT---AVPASDSPSAKQDVKKAGE- 139

  Fly   396 MRAILERERRERE-----------LEMLDETASLGGGGGRRGAGSSARARRAGSAGSGSSSAAGI 449
             |..|.:||||..           ||..::..:|     |.......|.|............|.:
  Rat   140 -RHKLAKERREERAKYLAAKKAVWLEKEEKAKAL-----REKQLQERRRRLEEQRLKAEQRRAAL 198

  Fly   450 MSRSMTHLAGGGGQRERGKYSLGGGISTSFRPLASGAGGQRDSTSKSMTQI--SSWSVYGSTAPQ 512
            ..|....|     ::.:.:|.               |..|| |..|:..:|  ..||..|:
  Rat   199 EERQRQKL-----EKNKERYE---------------AAIQR-SVKKTWAEIRQQRWSWAGA---- 238

  Fly   513 QPPPNHLHHLRQSTLGLQTAATK---------KYLQS------SFASASSFNSASFRANATGRGR 562
                  |||   ::.|.:|:.::         |::.|      |.:||:.:||.|         |
  Rat   239 ------LHH---NSPGRKTSGSRCSVSAVNLPKHVDSIINKRLSKSSATLWNSPS---------R 285

  Fly   563 QQQYAISTNPHRFLD--LDPNSLLLMNSASLLV------NAGSRSG------------NATPGGH 607
            .:...:|......:|  :.|....|..|.|.:.      :.|..||            :..||.|
  Rat   286 NRSLQLSAWESSIVDRLMTPTLSFLARSRSAVTLPRNGRDQGRGSGPGRRPTRARAGASLAPGPH 350

  Fly   608 FNNSRPGSAMSTSTNMSTSGLVPRRPATAP---------------RKPRPASIAGTGMS------ 651
            .:.:.|.:|:......:::.  |..|.:||               |||      |.|.|
  Rat   351 PDRTHPSAAVPVCPRSASAS--PLTPCSAPRSAHRCTPSGERPERRKP------GAGGSPALVRR 407

  Fly   652 -LEEINKLKRDQKPPVKTTAASPSAQTTPKRTANLMSTSLIVTSSSSRLSS-AEKKTPSKREPPV 714
             ||.....|:::|...:......||..   |..||.....:..|...|:|: ||..|.||..|..
  Rat   408 RLEATPVQKKEKKDKERENEKEKSALA---RERNLKKRQSLPASIRPRISTGAELSTKSKARPTS 469

  Fly   715 PK------AASASKALPSRTASSERISRLTKEPKTKDTSAMTRSMIVTSSSTSTITKPAPAPVAP 773
            |.      |:......|..|..       .|.|..:.|:|..:..|.....    .|.:|:|..
  Rat   470 PSTTWHRPASPCPSPGPGHTLP-------PKPPSPRGTTASPKGRIRRKEE----AKESPSPSG- 522

  Fly   774 TSAPVPEQNGVAKEVEKTTADEPVPEAEV-PTEAPVVVPSVSKAEKEALNTEKTEEGARQEEEQI 837
                 ||....:|   ..||:|..|.|.. |..:||..|:.::.:||..:|:...:
  Rat   523 -----PEDKNHSK---SRTAEEKEPAAPASPAPSPVPSPTPAQPQKEQSSTQIPPD--------- 570

  Fly   838 LAVESVPEALVTSINVEEKSDEGNEKEVPKPQEQAAPKKPSRSKENSEVRELTPPEGADLMTASM 902
            .||.:||                           ..|..|:           .||..|..:|.|.
  Rat   571 TAVPAVP---------------------------TVPTFPT-----------APPTAAPSVTPSK 597

  Fly   903 MAKKITTEEEAKAALAERRRLAREEAERQAELERQRLEAERLAEIKAQEEEAERQRLFEEESTRL 967
            .....|..|||...|||:||.|||:.||: |.|| :|:|||            .:|:.||:..|
  Rat   598 PMAGTTDREEATRLLAEKRRQAREQRERE-EQER-KLQAER------------DKRMREEQLAR- 647

  Fly   968 AEEQRRGEEERLRKAIEEAQQREEEEKRRR---EEEEKQRV--EREEAEKKAKEEAEKQRVEVAE 1027
             |.:.|.|.|      .||::|||:|.|.:   |:||::|:  ::||||.:::||||:||:|..:
  Rat   648 -EAEARAERE------AEARRREEQEAREKAQAEQEEQERLQKQKEEAEARSREEAERQRLEREK 705

  Fly  1028 RLKREEKEREERRKRVEAIMLRTRKGGAATTPSKDANDKAAPAATAPENNSSSNSSVTGSSNNSA 1092
            ..::||:||:|||||:|.||.||||..||.|..:|..:..|                    |||.
  Rat   706 HFQKEEQERQERRKRLEEIMKRTRKSEAAETKKQDGKETMA--------------------NNSG 750

  Fly  1093 EGSPSAADSTPAPTATETVQEAPNSQAMYEQSVLDKE--NSLINSFSTM-IIDENA--------- 1145
            .....|.::.|:....:::|:...:....:.|:..||  .||:|....: ...||.
  Rat   751 PDPVKAVETRPSGLQKDSMQKEELAPQEPQWSLPSKEMPGSLVNGLQPLPAHQENGFPAKGTAGD 815

  Fly  1146 KNLQQVSNGKL 1156
            |:|.:.:.|.|
  Rat   816 KSLGRAAEGLL 826

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ens	NP_001097498.1	MAP7	920..1060	CDD:283355	63/144 (44%)
Map7d1	XP_006238963.1	NAM-associated	93..211	CDD:291001	29/135 (21%)
Map7d1	XP_006238963.1	MAP7	592..738	CDD:283355	72/167 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166337500
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR15073
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030