DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Chd64 and Cnn1

DIOPT Version :9

Sequence 1:	NP_647860.1	Gene:	Chd64 / 38490	FlyBaseID:	FBgn0035499	Length:	188	Species:	Drosophila melanogaster
Sequence 2:	NP_113935.2	Gene:	Cnn1 / 65204	RGDID:	621883	Length:	297	Species:	Rattus norvegicus

Alignment Length:	189	Identity:	75/189 - (39%)
Similarity:	110/189 - (58%)	Gaps:	11/189 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 NRAAKSGFAAEAQRKINSKYSEELAQESLEWIKAVTEEPINTSGDTDNFFEVLKDGVILCKLANA 68
            ||....|.:||.:.|:..||..:..||..|||:.||...|.:     ||.:.||||:|||:..|.
  Rat     7 NRGPAYGLSAEVKNKLAQKYDHQREQELREWIEGVTGRRIGS-----NFMDGLKDGIILCEFINK 66

  Fly    69 LQPGSIKKINESKMAFKCMENISAFLACAKNFGVPTQETFQSVDLWERQN---LNSVVICLQSLG 130
            |||||:||:|||...:..:|||..|:.....:||...:.|::.||:|..|   :.|.::.|.|:.
  Rat    67 LQPGSVKKVNESTQNWHQLENIGNFIKAITKYGVKPHDIFEANDLFENTNHTQVQSTLLALASMA 131

  Fly   131 RKASNFNKPSIGPKEADKNVRNFSDEQLRAGANVISLQYGSNKGATQSGIN-FGNTRHM 188
            :  :..||.::|.|.|:|..|.|..|:||.|.|:|.||.|:||.|:|.|:. :|..||:
  Rat   132 K--TKGNKVNVGVKYAEKQERRFEPEKLREGRNIIGLQMGTNKFASQQGMTAYGTRRHL 188

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Chd64	NP_647860.1	CH_SF	22..131	CDD:412120	44/111 (40%)
Chd64	NP_647860.1	Calponin	165..187	CDD:395325	10/22 (45%)
Cnn1	NP_113935.2	CH_CNN1	27..134	CDD:409131	42/113 (37%)
		Calponin-like 1	164..189		12/25 (48%)
		Calponin	164..188	CDD:395325	11/23 (48%)
		Calponin-like 2	204..229
		Calponin	204..228	CDD:395325
		Calponin-like 3	243..268
		Calponin	244..267	CDD:395325
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166338530
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5199
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	136	1.000	Inparanoid score	I4455
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D488325at33208
OrthoFinder	1	1.000	-	-		FOG0000270
OrthoInspector	1	1.000	-	-		mtm8915
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X194
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.800