DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Chd64 and cnn1b

DIOPT Version :9

Sequence 1:	NP_647860.1	Gene:	Chd64 / 38490	FlyBaseID:	FBgn0035499	Length:	188	Species:	Drosophila melanogaster
Sequence 2:	XP_701038.5	Gene:	cnn1b / 572250	ZFINID:	ZDB-GENE-091118-54	Length:	296	Species:	Danio rerio

Alignment Length:	183	Identity:	70/183 - (38%)
Similarity:	106/183 - (57%)	Gaps:	9/183 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 GFAAEAQRKINSKYSEELAQESLEWIKAVTEEPINTSGDTDNFFEVLKDGVILCKLANALQPGSI 74
            |.:||.:.|:..||..:..:|...||..||...:     .:||.|.|||||:||:|.|.|||||:
Zfish    12 GLSAEVKSKLAHKYDPQKEEELRMWISDVTGRKL-----PENFMEGLKDGVLLCELINTLQPGSV 71

  Fly    75 KKINESKMAFKCMENISAFLACAKNFGVPTQETFQSVDLWERQN---LNSVVICLQSLGRKASNF 136
            :|||.|...:..:|||..|:...:.:|:...|.|::.||:|..|   :.|.:|.|..:.:.....
Zfish    72 RKINNSPQNWHQLENIGNFVRAIQEYGLKPHEIFEANDLFENVNHTQVQSTLIALAGMAKSKGFH 136

  Fly   137 NKPSIGPKEADKNVRNFSDEQLRAGANVISLQYGSNKGATQSGI-NFGNTRHM 188
            :|..||.|.|:|..|.|:.|:|:.|.|:|.||.|:||.|:|.|: ::|..||:
Zfish   137 SKYDIGVKYAEKQQRRFAPEKLKEGRNIIGLQMGTNKFASQKGMTSYGTRRHL 189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Chd64	NP_647860.1	CH_SF	22..131	CDD:412120	42/111 (38%)
Chd64	NP_647860.1	Calponin	165..187	CDD:395325	10/22 (45%)
cnn1b	XP_701038.5	SCP1	17..179	CDD:227526	63/166 (38%)
		CH	30..126	CDD:278723	39/100 (39%)
		Calponin	165..188	CDD:278814	10/22 (45%)
		Calponin	205..228	CDD:278814
		Calponin	245..267	CDD:278814
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578022
Domainoid	1	1.000	83	1.000	Domainoid score	I8268
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	135	1.000	Inparanoid score	I4555
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D488325at33208
OrthoFinder	1	1.000	-	-		FOG0000270
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X194
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.900