DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Chd64 and Cnn3

DIOPT Version :9

Sequence 1:	NP_647860.1	Gene:	Chd64 / 38490	FlyBaseID:	FBgn0035499	Length:	188	Species:	Drosophila melanogaster
Sequence 2:	XP_038958917.1	Gene:	Cnn3 / 54321	RGDID:	71044	Length:	374	Species:	Rattus norvegicus

Alignment Length:	174	Identity:	67/174 - (38%)
Similarity:	102/174 - (58%)	Gaps:	9/174 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 INSKYSEELAQESLEWIKAVTEEPINTSGDTDNFFEVLKDGVILCKLANALQPGSIKKINESKMA 83
            |.|||.::..::...||:.||...|.|     ||...||||:|||:|.|.|||||:||:|||.:.
  Rat    64 IASKYDQQAEEDLRNWIEEVTGMGIGT-----NFQLGLKDGIILCELINKLQPGSVKKVNESSLN 123

  Fly    84 FKCMENISAFLACAKNFGVPTQETFQSVDLWERQNLNSV---VICLQSLGRKASNFNKPSIGPKE 145
            :..:|||..|:...:.:|:...:.|::.||:|..|:..|   ::.|..|.:.........||.|.
  Rat   124 WPQLENIGNFIKAIQAYGMKPHDIFEANDLFENGNMTQVQTTLVALAGLAKTKGFHTTIDIGVKY 188

  Fly   146 ADKNVRNFSDEQLRAGANVISLQYGSNKGATQSGIN-FGNTRHM 188
            |:|..|.|.:.:|:||.:||.||.|:||.|:|:|:. :|..||:
  Rat   189 AEKQTRRFDEGKLKAGQSVIGLQMGTNKCASQAGMTAYGTRRHL 232

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Chd64	NP_647860.1	CH_SF	22..131	CDD:412120	42/111 (38%)
Chd64	NP_647860.1	Calponin	165..187	CDD:395325	10/22 (45%)
Cnn3	XP_038958917.1	CH_CNN3	67..177	CDD:409133	42/114 (37%)
		Calponin	208..232	CDD:395325	11/23 (48%)
		Calponin	248..272	CDD:395325
		Calponin	287..311	CDD:395325
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5199
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H37533
Inparanoid	1	1.050	136	1.000	Inparanoid score	I4455
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D488325at33208
OrthoFinder	1	1.000	-	-		FOG0000270
OrthoInspector	1	1.000	-	-		mtm8915
orthoMCL	1	0.900	-	-		OOG6_102866
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X194
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.770