DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Chd64 and cnn2

DIOPT Version :9

Sequence 1:	NP_647860.1	Gene:	Chd64 / 38490	FlyBaseID:	FBgn0035499	Length:	188	Species:	Drosophila melanogaster
Sequence 2:	XP_021335293.1	Gene:	cnn2 / 406658	ZFINID:	ZDB-GENE-030131-542	Length:	337	Species:	Danio rerio

Alignment Length:	223	Identity:	74/223 - (33%)
Similarity:	115/223 - (51%)	Gaps:	47/223 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 NRAAKSGFAAEAQRKINSKYSEELAQESLEWIKAVTEEPINTSGDT--DNFFEVLKDGVILCKLA 66
            ||....||:||.:.||..||..:..:|...||:       ||:|.:  |:|.:.||:|||||:|.
Zfish     6 NRGPAYGFSAEVKSKIAQKYDPQREEELRIWIE-------NTTGRSIGDDFQKGLKNGVILCELI 63

  Fly    67 NALQPGSIKKINESKMAFKCMENISAFLACAKNFGVPTQETFQSVDLWERQNLNSV--------- 122
            |.|||||:||||:|...:..:||::.|:.....:|:...:.|::.||:|..|:..|
Zfish    64 NKLQPGSVKKINQSSQNWHQLENLTNFIKAITTYGLKPHDIFEANDLFENGNMTQVQTTLLALAG 128

  Fly   123 --------------------------VICLQSLGRKASNFNKPSIGPKEADKNVRNFSDEQLRAG 161
                                      ::|||:  :.....:...||.|.|::..|.|.||:::||
Zfish   129 MVSPVQSYHFTGEQPNLDISDCNYRFLLCLQA--KTKGIHSSVDIGVKYAERQERAFDDEKMKAG 191

  Fly   162 ANVISLQYGSNKGATQSGIN-FGNTRHM 188
            ..||.||.|:||.|:|:|:| :|..||:
Zfish   192 QCVIGLQMGTNKCASQAGMNAYGTRRHL 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Chd64	NP_647860.1	CH_SF	22..131	CDD:412120	42/145 (29%)
Chd64	NP_647860.1	Calponin	165..187	CDD:395325	11/22 (50%)
cnn2	XP_021335293.1	CH	27..129	CDD:306753	37/108 (34%)
		Calponin	195..218	CDD:306832	11/22 (50%)
		Calponin	235..257	CDD:306832
		Calponin	274..296	CDD:306832
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578015
Domainoid	1	1.000	83	1.000	Domainoid score	I8268
eggNOG	1	0.900	-	-		E1_COG5199
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	135	1.000	Inparanoid score	I4555
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D488325at33208
OrthoFinder	1	1.000	-	-		FOG0000270
OrthoInspector	1	1.000	-	-		mtm6375
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2278
SonicParanoid	1	1.000	-	-		X194
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.830