DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Chd64 and Iqgap3

DIOPT Version :9

Sequence 1:	NP_647860.1	Gene:	Chd64 / 38490	FlyBaseID:	FBgn0035499	Length:	188	Species:	Drosophila melanogaster
Sequence 2:	NP_001028656.1	Gene:	Iqgap3 / 404710	MGIID:	3028642	Length:	1632	Species:	Mus musculus

Alignment Length:	140	Identity:	34/140 - (24%)
Similarity:	72/140 - (51%)	Gaps:	19/140 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 RAAKSGFAAE---AQRKINSKYSEELA--QESLEWIKAVTEEPINTSGDTDNFFEVLKDGVILCK 64
            |.|.....||   .||:.|..| :.|.  :|:..|::...:|.:.:..:.:   |.|::||:|.|
Mouse    10 RTAYERLTAEEMDEQRRQNVAY-QYLCRLEEAKRWMEVCLKEELPSPVELE---ESLRNGVLLAK 70

  Fly    65 LANALQPG--SIKKINE--------SKMAFKCMENISAFLACAKNFGVPTQETFQSVDLWERQNL 119
            |.:...|.  .:|||.:        :.:.|:..:||:.:|:...:.|:|:....::.|:::::|:
Mouse    71 LGHCFAPSVVPLKKIYDVEQLRYQATGLHFRHTDNINFWLSAVAHIGLPSIFLPETTDIYDKKNM 135

  Fly   120 NSVVICLQSL 129
            ..|:.|:.:|
Mouse   136 PRVIYCIHAL 145

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Chd64	NP_647860.1	CH_SF	22..131	CDD:412120	27/120 (23%)
Chd64	NP_647860.1	Calponin	165..187	CDD:395325
Iqgap3	NP_001028656.1	CH	35..147	CDD:237981	25/114 (22%)
		IQ	764..782	CDD:197470
		RasGAP	977..1328	CDD:214617
		RasGAP	988..1337	CDD:295371
		RasGAP_C	1434..1555	CDD:281787
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2278
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940