DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Chd64 and cnn3

DIOPT Version :9

Sequence 1:	NP_647860.1	Gene:	Chd64 / 38490	FlyBaseID:	FBgn0035499	Length:	188	Species:	Drosophila melanogaster
Sequence 2:	NP_989257.1	Gene:	cnn3 / 394869	XenbaseID:	XB-GENE-951266	Length:	331	Species:	Xenopus tropicalis

Alignment Length:	189	Identity:	76/189 - (40%)
Similarity:	113/189 - (59%)	Gaps:	9/189 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 NRAAKSGFAAEAQRKINSKYSEELAQESLEWIKAVTEEPINTSGDTDNFFEVLKDGVILCKLANA 68
            |:....|.:||.:.||..||..::.:|...||:.||...|.     :||.:.|:||:|||.|.|.
Frog     5 NKGPAYGLSAEVKNKIAQKYDPQVEEELRLWIEEVTGMIIG-----ENFQQGLRDGIILCNLINK 64

  Fly    69 LQPGSIKKINESKMAFKCMENISAFLACAKNFGVPTQETFQSVDLWERQNLNSVVICLQSLG--R 131
            |||||||||||:|:.:..:|||..|:...:::|:...:.|::.||:|..|:..|...|.||.  .
Frog    65 LQPGSIKKINEAKLNWHKLENIGNFIKAMQDYGMKPHDIFEANDLFENGNMTQVQTSLVSLAGLA 129

  Fly   132 KASNFN-KPSIGPKEADKNVRNFSDEQLRAGANVISLQYGSNKGATQSGIN-FGNTRHM 188
            |...|: ...||.|.|:|..|.|.||:::||.:||.||.|:||.|:|:|:. :|..||:
Frog   130 KTRGFHTSVDIGVKYAEKQKRQFGDEKMKAGQSVIGLQMGTNKCASQAGMTAYGTRRHL 188

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Chd64	NP_647860.1	CH_SF	22..131	CDD:412120	44/110 (40%)
Chd64	NP_647860.1	Calponin	165..187	CDD:395325	10/22 (45%)
cnn3	NP_989257.1	CH	27..126	CDD:366016	41/103 (40%)
		Calponin	164..187	CDD:366078	10/22 (45%)
		Calponin	204..226	CDD:366078
		Calponin	243..266	CDD:366078
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	85	1.000	Domainoid score	I8045
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H37533
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D488325at33208
OrthoFinder	1	1.000	-	-		FOG0000270
OrthoInspector	1	1.000	-	-		otm47470
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2278
SonicParanoid	1	1.000	-	-		X194
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.950