DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Chd64 and cnn3a

DIOPT Version :9

Sequence 1:	NP_647860.1	Gene:	Chd64 / 38490	FlyBaseID:	FBgn0035499	Length:	188	Species:	Drosophila melanogaster
Sequence 2:	NP_956047.1	Gene:	cnn3a / 326931	ZFINID:	ZDB-GENE-030131-5130	Length:	329	Species:	Danio rerio

Alignment Length:	189	Identity:	76/189 - (40%)
Similarity:	111/189 - (58%)	Gaps:	9/189 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 NRAAKSGFAAEAQRKINSKYSEELAQESLEWIKAVTEEPINTSGDTDNFFEVLKDGVILCKLANA 68
            |:....|.:||.:.||..||..:..:|...||:.||..||.     |:|.:.||||||||:|.|.
Zfish     5 NKGPAYGLSAEVKNKIAQKYDLQKEEELRFWIEEVTGMPIG-----DHFQKGLKDGVILCELINK 64

  Fly    69 LQPGSIKKINESKMAFKCMENISAFLACAKNFGVPTQETFQSVDLWERQNLNSV---VICLQSLG 130
            ||||||||||.|::.:..:||:..|:.....:|:...:.|::.||:|..|:..|   ::.|.|:.
Zfish    65 LQPGSIKKINHSQLNWHKLENLGNFIKAILAYGLKPNDIFEANDLFENGNMTQVQTTLLALASMA 129

  Fly   131 RKASNFNKPSIGPKEADKNVRNFSDEQLRAGANVISLQYGSNKGATQSGIN-FGNTRHM 188
            :.........||.|.|||..|||.||:::||..||.||.|:||.|:|:|:. :|..||:
Zfish   130 KTKGMETNIDIGVKYADKQQRNFDDEKMKAGQCVIGLQMGTNKCASQAGMTAYGTRRHL 188

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Chd64	NP_647860.1	CH_SF	22..131	CDD:412120	44/111 (40%)
Chd64	NP_647860.1	Calponin	165..187	CDD:395325	10/22 (45%)
cnn3a	NP_956047.1	SCP1	27..188	CDD:227526	67/165 (41%)
		CH	29..125	CDD:278723	40/100 (40%)
		Calponin	164..187	CDD:278814	10/22 (45%)
		Calponin	204..226	CDD:278814
		Calponin	243..266	CDD:278814
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	83	1.000	Domainoid score	I8268
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H37533
Inparanoid	1	1.050	135	1.000	Inparanoid score	I4555
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D488325at33208
OrthoFinder	1	1.000	-	-		FOG0000270
OrthoInspector	1	1.000	-	-		mtm6375
orthoMCL	1	0.900	-	-		OOG6_102866
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2278
SonicParanoid	1	1.000	-	-		X194
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	11	10.900