DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Chd64 and Tagln

DIOPT Version :9

Sequence 1:	NP_647860.1	Gene:	Chd64 / 38490	FlyBaseID:	FBgn0035499	Length:	188	Species:	Drosophila melanogaster
Sequence 2:	NP_035656.1	Gene:	Tagln / 21345	MGIID:	106012	Length:	201	Species:	Mus musculus

Alignment Length:	198	Identity:	73/198 - (36%)
Similarity:	110/198 - (55%)	Gaps:	12/198 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SNRAAKSGFAAEAQRKINSKYSEELAQESLEWIKAVTEEPINTSGDTDNFFEV-LKDGVILCKLA 66
            :|:....|.:.|.|.||..||.|||.:..:|||.......:.........|:| ||:||||.||.
Mouse     2 ANKGPSYGMSREVQSKIEKKYDEELEERLVEWIVVQCGPDVGRPDRGRLGFQVWLKNGVILSKLV 66

  Fly    67 NALQPGSIKKI----NESKMAFKCMENISAFLACAKNFGVPTQETFQSVDLWERQNLNSVVICLQ 127
            |:|.|...|.:    |...|.||.||.::.||..|:::||...:.||:|||:|.:::.:|...|.
Mouse    67 NSLYPEGSKPVKVPENPPSMVFKQMEQVAQFLKAAEDYGVIKTDMFQTVDLYEGKDMAAVQRTLM 131

  Fly   128 SLGRKASNFN------KPSIGPKEADKNVRNFSDEQLRAGANVISLQYGSNKGATQSGI-NFGNT 185
            :||..|...|      .|:...|:|.::.|:|:|.||:.|.:||.||.|||:||:|:|: .:|..
Mouse   132 ALGSLAVTKNDGNYRGDPNWFMKKAQEHKRDFTDSQLQEGKHVIGLQMGSNRGASQAGMTGYGRP 196

  Fly   186 RHM 188
            |.:
Mouse   197 RQI 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Chd64	NP_647860.1	CH_SF	22..131	CDD:412120	42/113 (37%)
Chd64	NP_647860.1	Calponin	165..187	CDD:395325	11/22 (50%)
Tagln	NP_035656.1	SCP1	14..189	CDD:227526	67/174 (39%)
		CH	25..137	CDD:237981	40/111 (36%)
		Calponin-like	175..200		12/25 (48%)
		Calponin	175..198	CDD:278814	11/22 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834945
Domainoid	1	1.000	84	1.000	Domainoid score	I8230
eggNOG	1	0.900	-	-		E1_COG5199
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	139	1.000	Inparanoid score	I4496
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D488325at33208
OrthoFinder	1	1.000	-	-		FOG0000270
OrthoInspector	1	1.000	-	-		mtm8680
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2278
SonicParanoid	1	1.000	-	-		X194
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	11	10.830