DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Chd64 and cpn-1

DIOPT Version :9

Sequence 1:	NP_647860.1	Gene:	Chd64 / 38490	FlyBaseID:	FBgn0035499	Length:	188	Species:	Drosophila melanogaster
Sequence 2:	NP_001369984.1	Gene:	cpn-1 / 172660	WormBaseID:	WBGene00000777	Length:	192	Species:	Caenorhabditis elegans

Alignment Length:	188	Identity:	107/188 - (56%)
Similarity:	138/188 - (73%)	Gaps:	2/188 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 ASNRAAKSGFAAEAQRKINSKYSEELAQESLEWIKAVTEEPINTSGDTDNFFEVLKDGVILCKLA 66
            :|:||.|||.|.|||:||..||.:.||.|.|:|::.||.:..:|.||.||..:|.:||.:||.||
Worm     6 SSDRAEKSGIALEAQQKIYEKYDKNLAGEILQWVQNVTGQSFDTQGDADNLVKVFQDGSLLCTLA 70

  Fly    67 NALQPGSIKKINESKMAFKCMENISAFLACAKNFGVPTQETFQSVDLWERQNLNSVVICLQSLGR 131
            |:|:|||:||:|.|.||||.|||||.||..|:.: |...|.||:|||:|.|:.|:|:|||.||.|
Worm    71 NSLKPGSVKKVNTSAMAFKKMENISFFLKFAEEY-VQKSELFQTVDLYEGQDPNAVLICLASLAR 134

  Fly   132 KA-SNFNKPSIGPKEADKNVRNFSDEQLRAGANVISLQYGSNKGATQSGINFGNTRHM 188
            |: .||.:..:|||||..:.|.::||||:||.|||.||.|||||||.||:|.||||||
Worm   135 KSEKNFGRSGLGPKEAQGDRREWTDEQLKAGHNVIGLQMGSNKGATASGLNMGNTRHM 192

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Chd64	NP_647860.1	CH_SF	22..131	CDD:412120	58/108 (54%)
Chd64	NP_647860.1	Calponin	165..187	CDD:395325	16/21 (76%)
cpn-1	NP_001369984.1	CH_dMP20-like	26..134	CDD:409056	58/108 (54%)
cpn-1	NP_001369984.1	Calponin	169..191	CDD:395325	16/21 (76%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166920
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5199
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	207	1.000	Inparanoid score	I2415
Isobase	1	0.950	-	0	Normalized mean entropy	S1711
OMA	1	1.010	-	-		QHG56098
OrthoDB	1	1.010	-	-		D488325at33208
OrthoFinder	1	1.000	-	-		FOG0000270
OrthoInspector	1	1.000	-	-		oto17217
orthoMCL	1	0.900	-	-		OOG6_102866
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2278
SonicParanoid	1	1.000	-	-		X194
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.690