DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Chd64 and Cnn2

DIOPT Version :9

Sequence 1:	NP_647860.1	Gene:	Chd64 / 38490	FlyBaseID:	FBgn0035499	Length:	188	Species:	Drosophila melanogaster
Sequence 2:	NP_031751.1	Gene:	Cnn2 / 12798	MGIID:	105093	Length:	305	Species:	Mus musculus

Alignment Length:	189	Identity:	72/189 - (38%)
Similarity:	106/189 - (56%)	Gaps:	9/189 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 NRAAKSGFAAEAQRKINSKYSEELAQESLEWIKAVTEEPINTSGDTDNFFEVLKDGVILCKLANA 68
            |:....|.:||.:.::.|||..:...|...||:.:|...|.     .:|.:.||||||||.|.|.
Mouse     7 NKGPSYGLSAEVKNRLLSKYDPQKEAELRSWIEGLTGLSIG-----PDFQKGLKDGVILCTLMNK 66

  Fly    69 LQPGSIKKINESKMAFKCMENISAFLACAKNFGVPTQETFQSVDLWERQNLNSVVICLQSLGRKA 133
            |||||:.|||.|...:..:||:|.|:....::|:...:.|::.||:|..|:..|.:.|.:|..||
Mouse    67 LQPGSVPKINRSMQNWHQLENLSNFIKAMVSYGMNPVDLFEANDLFESGNMTQVQVSLLALAGKA 131

  Fly   134 SNFNKPS---IGPKEADKNVRNFSDEQLRAGANVISLQYGSNKGATQSGIN-FGNTRHM 188
            ......|   ||.|.::|..|||.|..::||..||.||.|:||.|:|||:. :|..||:
Mouse   132 KTKGLQSGVDIGVKYSEKQERNFDDATMKAGQCVIGLQMGTNKCASQSGMTAYGTRRHL 190

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Chd64	NP_647860.1	CH_SF	22..131	CDD:412120	40/108 (37%)
Chd64	NP_647860.1	Calponin	165..187	CDD:395325	11/22 (50%)
Cnn2	NP_031751.1	SCP1	19..190	CDD:227526	67/175 (38%)
		CH	31..127	CDD:278723	37/100 (37%)
		Calponin-like 1	166..191		13/25 (52%)
		Calponin	166..189	CDD:278814	11/22 (50%)
		Calponin-like 2	206..231
		Calponin	206..229	CDD:278814
		Calponin-like 3	245..269
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834939
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5199
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D488325at33208
OrthoFinder	1	1.000	-	-		FOG0000270
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2278
SonicParanoid	1	1.000	-	-		X194
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.780