Protein Alignment Ack and Alk

DIOPT Version :10

• Sequence 1: NP_647859.1
• Gene: Ack / 38489
• FlyBaseID: FBgn0028484
• Length: 1073
• Species: Drosophila melanogaster
• Sequence 2: NP_652600.1
• Gene: Alk / 53425
• FlyBaseID: FBgn0040505
• Length: 1701
• Species: Drosophila melanogaster
• Alignment Length: 541
• Identity: 140/541 - (25%)
• Similarity: 215/541 - (39%)
• Gaps: 163/541 - (30%)

  Fly   129 LGDGSFGVV-----RRGEWSASPAGKVIPVAVKVLKSDNLTQPGIIDDFFREVQAMHALDHANLV 188
            ||.|:||.|     |..:..|...|    ||||.|:.|...:..  :||.:|...|...:|.|:|
  Fly  1199 LGKGAFGEVYMALYRHRDGDAVEMG----VAVKTLREDPKREKE--EDFLKEAAIMAKFNHPNMV 1257

  Fly   189 RLYGVVLS-QPMMMITELAERGSLLDTLRKQCRHTS-----LTI--IWNWSVQIVTGMAYLEQKR 245
            .|.||... ||..::.||...|.|...||:. |:|.     ||:  :...::.:..|..|:|.||
  Fly  1258 HLIGVCFDRQPYYIVLELLAGGDLQKFLREN-RNTPERPSLLTMKDLLFCALDVAKGCRYMESKR 1321

  Fly   246 FLHRDLACRNVLLAA---GNKIKIGDFGLMRALPQEDDCYVMSEHKKVPFPWCAPESLRFRQFSH 307
            |:|||:|.||.||::   |..:||.|||:.|.: ...|.|.......:|..|..||:.....|:.
  Fly  1322 FIHRDIAARNCLLSSKGPGRVVKIADFGMSRDI-YRSDYYRKGGKAMLPIKWMPPEAFLDGIFTS 1385

  Fly   308 ASDTWMFGVTLWEMFSFGEDPWVGLNGSQILRKIDREGERLHQPDACPPDVYAMMLQCWDKTPAE 372
            .:|.|.||:.|||:||.|..|:.|.:.:|::..:.| |.||..|..||..:|.:|..||:.||.:
  Fly  1386 KTDVWSFGILLWEVFSLGRSPYPGQHNTQVMELVVR-GGRLGSPTECPVSIYKVMADCWNPTPED 1449

  Fly   373 RPTFAALKEYLASMS----------PPVMRASRSHHESKGLQIEPGDTIAIIDGRHELKLIKGQN 427
            ||||..|.|:|.:.:          |.::..:.|         |..||:           |:..|
  Fly  1450 RPTFITLLEHLTACTQDASIMNAPLPNILGPTAS---------ERDDTV-----------IRPPN 1494

  Fly   428 QRTFDIGIFPRNLLEQRKVGAAGDVVMRSSVGNGSSSSPFGFCWGGAAAMANGD----DRQRKCA 488
            ...|.:.: |..|:               .:..|.|::|         :||:|.    :.||:..
  Fly  1495 GEEFCLAV-PDYLV---------------PLPPGGSNNP---------SMASGSGYVPELQRQQM 1534

  Fly   489 SMTNQPHAKERKSTSSKQFAYNKLVNDSATGLQRRNAVKHKGVVVGPQRPPPPQFQQEGILIDIS 553
            |....|                                    .|..|..|.|
  Fly  1535 SSCTPP------------------------------------AVTSPAAPHP------------- 1550

  Fly   554 PDMRPIAEAGTGGAKGAGDSSSLQADSSFCILDAPIDVPTYAGSSGSGDLNVSPTYYNEQPQFDF 618
               ||:...    |..:||.    .::||.:.::.::.|..    |||         ::.|....
  Fly  1551 ---RPVENI----APTSGDC----WETSFILPNSKVEPPVV----GSG---------HDVPLAGG 1591

  Fly   619 DPAKMTA------SPGRLQPP 633
            :.||:.:      :|..:|||
  Fly  1592 EEAKLISLDTPQPTPTTIQPP 1612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ack	NP_647859.1	SAM_TNK-like	14..75	CDD:188938
		PTKc_Ack_like	128..385	CDD:270636	98/271 (36%)
		UBA_TNK1	1031..1070	CDD:270513
Alk	NP_652600.1	MAM	288..447	CDD:99706
		MAM	505..689	CDD:99706
		PTKc_ALK_LTK	1186..1462	CDD:270632	98/271 (36%)