Protein Alignment Ack and htl

DIOPT Version :10

• Sequence 1: NP_647859.1
• Gene: Ack / 38489
• FlyBaseID: FBgn0028484
• Length: 1073
• Species: Drosophila melanogaster
• Sequence 2: NP_524394.2
• Gene: htl / 42160
• FlyBaseID: FBgn0010389
• Length: 729
• Species: Drosophila melanogaster
• Alignment Length: 411
• Identity: 121/411 - (29%)
• Similarity: 187/411 - (45%)
• Gaps: 87/411 - (21%)

  Fly    63 AIRRLM-EAVRKKK---AHQW-RKNILSKLIGGGKQPSS-----------KKQSSAARESSQGNG 111
            |||::. |.|.|::   .||| :|.|:.|..|||....|           :||.:...:    ||
  Fly   332 AIRKMKHEKVLKQRIETVHQWTKKVIIFKPEGGGDSSGSMDTMIMPVVRIQKQRTTVLQ----NG 392

  Fly   112 TQLTCL------------IHEKDITMGLKLGDGSFGVVRRGEWSASPAGKVIPVAVKVLKSDNLT 164
            .:....            :....:.:|..||:|:||.|...|     ....| ||||::|.
  Fly   393 NEPAPFNEYEFPLDSNWELPRSHLVLGATLGEGAFGRVVMAE-----VNNAI-VAVKMVKE---- 447

  Fly   165 QPGIIDD----FFREVQAMHALD-HANLVRLYGVVLSQ--PMMMITELAERGSLLDTL------- 215
              |..||    ..||::.|..:. |.|::.|.| ..||  |:.:|.|.|..|:|.|.|
  Fly   448 --GHTDDDIASLVREMEVMKIIGRHINIINLLG-CCSQNGPLYVIVEYAPHGNLKDFLYKNRPFG 509

  Fly   216 RKQCRHTS----------LT--IIWNWSVQIVTGMAYLEQKRFLHRDLACRNVLLAAGNKIKIGD 268
            |.|.|.:|          :|  .:..::.||..||.||..:|.:|||||.||||::....:||.|
  Fly   510 RDQDRDSSQPPPSPPAHVITEKDLIKFAHQIARGMDYLASRRCIHRDLAARNVLVSDDYVLKIAD 574

  Fly   269 FGLMRALPQEDDCYVMSEHKKVPFPWCAPESLRFRQFSHASDTWMFGVTLWEMFSFGEDPWVGLN 333
            |||.|.: |..|.|..:.:.::|..|.|||||:.:.:...||.|.:|:.|||:.::|:.|:..:.
  Fly   575 FGLARDI-QSTDYYRKNTNGRLPIKWMAPESLQEKFYDSKSDVWSYGILLWEIMTYGQQPYPTIM 638

  Fly   334 GSQILRKIDREGERLHQPDACPPDVYAMMLQCWDKTPAERPTFAALKEY---------------L 383
            .::.|......|:|:.:|..|..::|.:|.|||.....:||.|..:.||               :
  Fly   639 SAEELYTYLMSGQRMEKPAKCSMNIYILMRQCWHFNADDRPPFTEIVEYMDKLLQTKEDYLDVDI 703

  Fly   384 ASMSPPVMRASRSHHESKGLQ 404
            |::..|...:.....|:..||
  Fly   704 ANLDTPPSTSDEEEDETDNLQ 724

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ack	NP_647859.1	SAM_TNK-like	14..75	CDD:188938	6/12 (50%)
		PTKc_Ack_like	128..385	CDD:270636	95/297 (32%)
		UBA_TNK1	1031..1070	CDD:270513
htl	NP_524394.2	Ig	101..191	CDD:472250
		Ig strand B	121..125	CDD:409353
		Ig strand C	134..138	CDD:409353
		Ig strand E	157..161	CDD:409353
		Ig strand F	171..176	CDD:409353
		Ig strand G	184..187	CDD:409353
		Ig	200..289	CDD:472250
		Ig strand B	216..220	CDD:409353
		Ig strand C	229..233	CDD:409353
		Ig strand E	255..259	CDD:409353
		Ig strand F	269..274	CDD:409353
		Ig strand G	282..285	CDD:409353
		Protein Kinases, catalytic domain	404..692	CDD:473864	96/301 (32%)