Protein Alignment Ack and Src42A

DIOPT Version :10

• Sequence 1: NP_647859.1
• Gene: Ack / 38489
• FlyBaseID: FBgn0028484
• Length: 1073
• Species: Drosophila melanogaster
• Sequence 2: NP_001400996.1
• Gene: Src42A / 35524
• FlyBaseID: FBgn0264959
• Length: 1606
• Species: Drosophila melanogaster
• Alignment Length: 286
• Identity: 109/286 - (38%)
• Similarity: 156/286 - (54%)
• Gaps: 39/286 - (13%)

  Fly   120 EKDITMGL-------------------KLGDGSFGVVRRGEWSASPAGKVIPVAVKVLKSDNLTQ 165
            ||.:|.||                   |||.|.||.|..|.|:     ...|||:|.|||
  Fly  1315 EKPVTEGLSHRTRDQWEIDRTSLKFVRKLGSGQFGDVWEGLWN-----NTTPVAIKTLKS----- 1369

  Fly   166 PGIID--DFFREVQAMHALDHANLVRLYGV-VLSQPMMMITELAERGSLLDTLRK---QCRHTSL 224
             |.:|  ||..|.|.|..|.|..|::||.| .:.:|:.:||||.:.||||:.|:.   :.|...:
  Fly  1370 -GTMDPKDFLAEAQIMKKLRHTKLIQLYAVCTVEEPIYIITELMKHGSLLEYLQAIAGKGRSLKM 1433

  Fly   225 TIIWNWSVQIVTGMAYLEQKRFLHRDLACRNVLLAAGNKIKIGDFGLMRALPQEDDCYVMSEHKK 289
            ..:.:.:.||..||||||.:.::|||||.||||:..||.:||.||||.|.:  ::|.|......:
  Fly  1434 QTLIDMAAQIAAGMAYLESQNYIHRDLAARNVLVGDGNIVKIADFGLARLI--KEDEYEARVGAR 1496

  Fly   290 VPFPWCAPESLRFRQFSHASDTWMFGVTLWEMFSFGEDPWVGLNGSQILRKIDREGERLHQPDAC 354
            .|..|.|||:..:.:||..||.|.||:.|.|:.::|..|:.|:..:::|.::: .|.|:.||..|
  Fly  1497 FPIKWTAPEAANYSKFSIKSDVWSFGILLTELVTYGRIPYPGMTNAEVLTQVE-HGYRMPQPPNC 1560

  Fly   355 PPDVYAMMLQCWDKTPAERPTFAALK 380
            .|.:|.:||:||.|.|..||||..|:
  Fly  1561 EPRLYEIMLECWHKDPMRRPTFETLQ 1586

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ack	NP_647859.1	SAM_TNK-like	14..75	CDD:188938
		PTKc_Ack_like	128..385	CDD:270636	104/259 (40%)
		UBA_TNK1	1031..1070	CDD:270513
Src42A	NP_001400996.1	SH2_Src_Src42	1210..1301	CDD:198233
		PTKc_Frk_like	1328..1596	CDD:270653	104/273 (38%)