Protein Alignment Ack and Tnk1

DIOPT Version :9

• Sequence 1: NP_647859.1
• Gene: Ack / 38489
• FlyBaseID: FBgn0028484
• Length: 1073
• Species: Drosophila melanogaster
• Sequence 2: XP_006246766.1
• Gene: Tnk1 / 303247
• RGDID: 1310113
• Length: 740
• Species: Rattus norvegicus
• Alignment Length: 599
• Identity: 219/599 - (36%)
• Similarity: 308/599 - (51%)
• Gaps: 59/599 - (9%)

  Fly    13 SETAWLEDLLREVQLEQFLDRIRDDLQVTRLAHFDYVLPDDLERCGLGKPAIRRLMEAVRKKKAH 77
            :.:.||..|||:|||.||...|.::|.|||..|||:|.|:||:..|:|:||.|||.||:::.::.
  Rat    78 ASSLWLLRLLRDVQLAQFYRPILEELNVTRPEHFDFVRPEDLDNLGMGRPAQRRLTEALKRYRSG 142

  Fly    78 QWRKNILSKLIGG--GKQPSSKKQSSAARESSQGNGTQLTCLIHEKDITMGLKLGDGSFGVVRRG 140
            ...||.:.|::||  .:|......|.:.....:..| .|.|||.|..:..|..||.|.||||.:|
  Rat   143 VKSKNWVYKILGGFAPEQKEIPPYSDSLPHLHEPEG-GLKCLIPEGAVCRGELLGSGCFGVVHQG 206

  Fly   141 EWSASPAGKVIPVAVKVLKSDNLTQPGI-IDDFFREVQAMHALDHANLVRLYGVVLSQPMMMITE 204
            .|:. |.|:.||||||.|:.......|. :.||.|||..|..|:|.:::||:|:||.||:.|:.|
  Rat   207 LWTL-PGGQSIPVAVKSLRVGPEGPMGTELGDFLREVSVMMKLEHPHVLRLHGLVLGQPLQMVME 270

  Fly   205 LAERGSLLDTLRKQCRHTS--------LTIIWNWSVQIVTGMAYLEQKRFLHRDLACRNVLLAAG 261
            ||..|||      ..|.|:        :|::..:..|:...||||.....:|||||.||:|||:.
  Rat   271 LAPLGSL------HARLTAPAPMPPLPVTLLCLFLRQLAGAMAYLGSCGLVHRDLATRNLLLASP 329

  Fly   262 NKIKIGDFGLMRALPQEDDCYVMSEHKKVPFPWCAPESLRFRQFSHASDTWMFGVTLWEMFSFGE 326
            .|||:.||||:|.|......|||...:.:|:.||||||||...||.|||.||||||||||||.||
  Rat   330 RKIKVADFGLVRPLGGARGRYVMGGPRPIPYAWCAPESLRQGAFSAASDVWMFGVTLWEMFSGGE 394

  Fly   327 DPWVGLNGSQILRKIDREGERLHQPDACPPDVYAMMLQCWDKTPAERPTFAALKEYLASMSPPVM 391
            :||.|:....||::::::..||.:|..|...:|::.|:||...||:||||:.|:..|........
  Rat   395 EPWAGVPPYLILQRLEKDRARLPKPALCSRALYSLALRCWAPHPADRPTFSNLEGLLQEAWLSEG 459

  Fly   392 RASRSHHESKGLQIEPGDTIAIIDGRHELKLIKGQNQRTFDIGIFPRNLLEQRKVGAA--GDVVM 454
            |..|...|...|::||||.|.||:|..:....||||.||..:|.||.:.:....:|.:  ...|.
  Rat   460 RCVREVTEPGALRMEPGDPITIIEGSPDTTTWKGQNGRTLKVGNFPASAVTLADLGGSPVTHPVH 524

  Fly   455 RSSVGNGSSSSPFGFCWGGAAAMANGDDRQRKCASMTNQPHAK--ERKSTSSKQFAYNKLVND-- 515
            |.|...|..             ...|.|..|:.|.:.:.|.|:  .||....:....:|.:..
  Rat   525 RGSPARGEK-------------YRGGTDGDREKAVLQDLPPARNQRRKVPLQRMKGISKSLESVL 576

  Fly   516 ----------SATGLQRRNAVK--HKGVVVGPQRPP--PPQFQQEGILIDISP----DMRPIAEA 562
                      |:....||...:  .:|:...|.|||  ||   :..|:....|    .:||..|.
  Rat   577 SLGPRPAGGGSSPPELRRGCTRAWPQGLADLPPRPPDLPP---RPPIICSSQPIQPHRVRPKREP 638

  Fly   563 GTGGAKGAGDSSSL 576
            ......||..||.:
  Rat   639 LHNHCTGAPGSSKV 652

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ack	NP_647859.1	SAM_TNK-like	14..75	CDD:188938	31/60 (52%)
		PTKc_Ack_like	128..385	CDD:270636	120/265 (45%)
		UBA_TNK1	1031..1070	CDD:270513
Tnk1	XP_006246766.1	SAM_TNK-like	89..140	CDD:188938	26/50 (52%)
		STYKc	192..451	CDD:214568	120/265 (45%)
		PKc_like	193..453	CDD:304357	120/266 (45%)
		UBA_like_SF	668..711	CDD:304366
		UBA_like_SF	698..737	CDD:304366

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	89	1.000	Domainoid score	I7694
eggNOG	1	0.900	-	-		E1_KOG0199
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1008736at2759
OrthoFinder	1	1.000	-	-		FOG0002936
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24418
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.920