Protein Alignment Ack and T21G5.1

DIOPT Version :10

• Sequence 1: NP_647859.1
• Gene: Ack / 38489
• FlyBaseID: FBgn0028484
• Length: 1073
• Species: Drosophila melanogaster
• Sequence 2: NP_001355382.1
• Gene: T21G5.1 / 266839
• WormBaseID: WBGene00020659
• Length: 514
• Species: Caenorhabditis elegans
• Alignment Length: 308
• Identity: 100/308 - (32%)
• Similarity: 160/308 - (51%)
• Gaps: 26/308 - (8%)

  Fly   115 TCLIHEKDITMGLKLGDGSFGVVRRGEWSASPAGKVIPVAVKVLKSDNLTQPGIID---DFFREV 176
            |.:|..:|:.:..|:|.|:||.|.........:..|:..|||.||     |...:|   .|.:|.
 Worm   181 TWIIPHEDVILYRKIGSGAFGEVFLARMVDPTSEYVLDCAVKKLK-----QEATMDAKLRFMKEA 240

  Fly   177 QAM-HALDHANLVRLYGV-VLSQPMMMITELAERGSLLDTLRKQCRHTSLTIIWNWSVQIVTGMA 239
            :.| ....|.::|.::|: .|:.|::::.||...|||:..|||.....:|.....:|.:..:|:|
 Worm   241 RMMLKNYKHKHIVMIFGIATLNSPLLILMELCPNGSLISYLRKNKGKVTLLEKLRFSAEASSGLA 305

  Fly   240 YLEQKRFLHRDLACRNVLLAAGNKIKIGDFGLMRALPQEDDCYVMSEHK--KVPFPWCAPESLRF 302
            |||:...:|||:|.||.||:|.|:|||.|.||      .||..::.::.  |:|..|.|||.::.
 Worm   306 YLEKMECIHRDIAARNCLLSAKNEIKISDLGL------ADDKGMVIDYSLDKLPIKWLAPEIMQD 364

  Fly   303 RQFSHASDTWMFGVTLWEMFSFGEDPWVGLNGSQILRKIDREGERLHQPDACPPDVYAMMLQCWD 367
            :.:|..||.|.||:.:||:|:.|::|:.|||.:|...||.....|:..||..|.::..::..||.
 Worm   365 KVYSLKSDIWAFGIMIWEIFAEGDEPYPGLNNTQARAKIVVLDYRMKFPDEAPTELVQVIDTCWK 429

  Fly   368 KTPAERPTF---AALKEYLASMSPPVMRASRSHHESKGLQIEPGDTIA 412
            |.|..|.|.   ::..:.|.....|::.|......|    :.|| |||
 Worm   430 KDPDMRQTMVLHSSALQLLYENKLPLLFAQTIQATS----LPPG-TIA 472

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ack	NP_647859.1	SAM_TNK-like	14..75	CDD:188938
		PTKc_Ack_like	128..385	CDD:270636	89/266 (33%)
		UBA_TNK1	1031..1070	CDD:270513
T21G5.1	NP_001355382.1	SH2_Fps_family	72..165	CDD:198224
		STYKc	189..438	CDD:214568	87/259 (34%)