Protein Alignment Ack and frk-1

DIOPT Version :10

• Sequence 1: NP_647859.1
• Gene: Ack / 38489
• FlyBaseID: FBgn0028484
• Length: 1073
• Species: Drosophila melanogaster
• Sequence 2: NP_001369901.1
• Gene: frk-1 / 191635
• WormBaseID: WBGene00001487
• Length: 390
• Species: Caenorhabditis elegans
• Alignment Length: 339
• Identity: 106/339 - (31%)
• Similarity: 167/339 - (49%)
• Gaps: 49/339 - (14%)

  Fly    77 HQWRKNILSKLIG---GGKQPSSKKQSSAARESSQGNGTQLTCLIHEKDITMGLKLGDGSFGVVR 138
            |..:::.:|:||.   ..|.|.|....:..|...:    :...||:...|....|||:|:||.|.
 Worm    86 HTHQESTISELINWHMTTKTPISAASGAKIRRPME----RSPWLINHDSIVANKKLGEGAFGDVF 146

  Fly   139 RGEWSASPAGKVIPVAVKVLKSDNLTQPGIIDDFFREVQAMHALDHANLVRLYGVVLSQ-PMMMI 202
            ..|  ....||. .||||.::::...:..:  .|.:|.:.|....|.::|:|.||.:.: |:|::
 Worm   147 IAE--LDQGGKQ-EVAVKTMRAEATREARL--RFMKEARLMRKYQHKHVVKLIGVAIHEHPLMIV 206

  Fly   203 TELAERGSLLDTLRKQCRHTSLTIIWNWSVQIVTGMAYLEQKRFLHRDLACRNVLLAAGNKIKIG 267
            .|....||||..|:|  ...||.....::.:...|:||||:.:.:|||:|.||.||:|.|::||.
 Worm   207 MEYCPNGSLLSHLKK--NKVSLIEKLRFTTEAADGIAYLERSKCIHRDIAARNCLLSAKNELKIS 269

  Fly   268 DFGLMRALPQEDDCYVMSEHK---------KVPFPWCAPESLRFRQFSHASDTWMFGVTLWEMFS 323
            |||             ||::|         |||..|.|||:::.:.::|.:|.|.|||.:||::|
 Worm   270 DFG-------------MSDNKDEIKDETLEKVPIKWLAPETMQEKVYTHKTDIWTFGVLVWEIYS 321

  Fly   324 FGEDPWVGLNGSQILRKIDREGERLHQPDACPPDVYAMML-QCWDKTPAERPTFAALKEYLASMS 387
            .|.:|:.||...|...||.....|:..||...|.|..::. .||.|.|.:|.|..::.:.|
 Worm   322 DGAEPYPGLTKIQTRAKIVVNDYRMKMPDGTHPTVADVVTGTCWQKNPEKRSTMDSIHKKL---- 382

  Fly   388 PPVMRASRSHHESK 401
                   |..:|||
 Worm   383 -------REFYESK 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ack	NP_647859.1	SAM_TNK-like	14..75	CDD:188938
		PTKc_Ack_like	128..385	CDD:270636	91/267 (34%)
		UBA_TNK1	1031..1070	CDD:270513
frk-1	NP_001369901.1	SH2_Fps_family	16..107	CDD:198224	5/20 (25%)
		TyrKc	131..382	CDD:197581	91/270 (34%)