Protein Alignment Ack and F59A3.8

DIOPT Version :10

• Sequence 1: NP_647859.1
• Gene: Ack / 38489
• FlyBaseID: FBgn0028484
• Length: 1073
• Species: Drosophila melanogaster
• Sequence 2: NP_491620.2
• Gene: F59A3.8 / 186579
• WormBaseID: WBGene00019081
• Length: 577
• Species: Caenorhabditis elegans
• Alignment Length: 273
• Identity: 95/273 - (34%)
• Similarity: 148/273 - (54%)
• Gaps: 19/273 - (6%)

  Fly   119 HEKDITMGLKLGDGSFGVVRRGEWSA-SPAGKVIPVAVKVLKS--DNLTQPGIIDDFFREVQAMH 180
            ||....:..|||:|:||.||.|..:. .|..|::.||||:|||  |::|:.. :::...|.:.|.
 Worm   306 HEDTELLAKKLGEGAFGEVRVGRLTTKDPKKKLVEVAVKMLKSSADSVTRDQ-VEELLHETRIMR 369

  Fly   181 ALDHANLVRLYGV-VLSQPMMMITELAERGSLLDTLRKQCRHTSLTIIWNWSVQIVTGMAYLEQK 244
            .|||.|::|.||| ||.:|:.::.||...|:|.:.|::..:..:|....|:.:....|:|||..:
 Worm   370 KLDHPNVLRSYGVAVLREPLYLMIELCSNGALREYLKENHKTITLADKINFVLGSARGVAYLHSQ 434

  Fly   245 RFLHRDLACRNVLLAAGNKIKIGDFGLMRALPQEDDCYVMSEHKKVPFPWCAPESLRFRQFSHAS 309
            |.||||||.||:||......|:.|||    |.:..|.|.|.||.|:|..:.|||:|....|:..:
 Worm   435 RILHRDLAVRNILLTEDKTPKVSDFG----LAELTDRYEMKEHCKIPVRYLAPETLELFIFTPKT 495

  Fly   310 DTWMFGVTLWEMFSFGEDPWVGLNGSQILRKIDREGERLHQPDACPPDVYAMMLQCWDKTPAERP 374
            |.:.||..:||::..|:.|..|.| :|.:|...::.|.|....:.|..:..::        ||:
 Worm   496 DVFSFGCVIWEIYENGQQPHDGKN-AQTIRAQVKKREFLKLSSSAPEALRRLV--------AEK- 550

  Fly   375 TFAALKEYLASMS 387
            .|.|..|...||:
 Worm   551 VFVADPENRCSMT 563

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ack	NP_647859.1	SAM_TNK-like	14..75	CDD:188938
		PTKc_Ack_like	128..385	CDD:270636	91/260 (35%)
		UBA_TNK1	1031..1070	CDD:270513
F59A3.8	NP_491620.2	SH2	165..286	CDD:472789
		TyrKc	312..568	CDD:197581	93/267 (35%)