Protein Alignment Ack and kin-26

DIOPT Version :10

• Sequence 1: NP_647859.1
• Gene: Ack / 38489
• FlyBaseID: FBgn0028484
• Length: 1073
• Species: Drosophila melanogaster
• Sequence 2: NP_501309.1
• Gene: kin-26 / 177575
• WormBaseID: WBGene00002208
• Length: 433
• Species: Caenorhabditis elegans
• Alignment Length: 305
• Identity: 95/305 - (31%)
• Similarity: 150/305 - (49%)
• Gaps: 28/305 - (9%)

  Fly    94 PSSKKQSSAARESSQGNGTQLT--CLI------------HEKDITMGLKLGDGSFGVVRRGEWSA 144
            ||.:|...    :.|.|.|::.  |::            |:: ||:..|||:|:||.|..|....
 Worm    92 PSIQKMLG----TYQRNNTEIKEGCMLVNPIRRQFWELEHDQ-ITIHKKLGEGAFGEVSSGVMKF 151

  Fly   145 SPAGKVIPVAVKVLKSDNLTQPGIIDDFFREVQAMHALDHANLVRLYGV-VLSQPMMMITELAER 208
            ....|.:.||:|.:|.|. |....|.||..|.:.|..|.|.|:::.||| ||.:|:.::.|||..
 Worm   152 KKGMKTVQVAIKQVKLDK-TGKAKIKDFLAEARTMRKLGHQNIIKFYGVGVLQEPLYLVMELAVN 215

  Fly   209 GSLLDTLRKQCRHTSLTIIWNWSVQIVTGMAYLEQKRFLHRDLACRNVLLAAGNKIKIGDFGLMR 273
            |: ||:..|:....|:.......:|...|:.|:..|..||||:|.||.|...| |:||.||||.|
 Worm   216 GA-LDSFLKKNEDLSVDKKTEMILQAAWGLEYIHGKPMLHRDIAARNCLYTDG-KVKISDFGLTR 278

  Fly   274 ALPQEDDCYVMSEHKKVPFPWCAPESLRFRQFSHASDTWMFGVTLWEMFSFGEDPWVGLNGSQIL 338
                ....|.:..:.|.|..|.|.|:::....|..:|.|.:||..||:|:...:|:.|:..:.:.
 Worm   279 ----NGTVYQIKPNTKSPIRWLAIETIKTMICSEKTDVWAYGVLCWEIFNNAAEPYPGMKPADVA 339

  Fly   339 RKIDREGERLHQPDACPPDVYAMMLQCWDKTPAERPTFAALKEYL 383
            .:: ..|.|:........::..||.:|..:.|.:||:.|.:.|.|
 Worm   340 TQV-ANGYRMPPYPHAQAEIQTMMARCNAENPNDRPSMAEIAEIL 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ack	NP_647859.1	SAM_TNK-like	14..75	CDD:188938
		PTKc_Ack_like	128..385	CDD:270636	85/257 (33%)
		UBA_TNK1	1031..1070	CDD:270513
kin-26	NP_501309.1	SH2_Fps_family	15..108	CDD:198224	6/19 (32%)
		TyrKc	130..383	CDD:197581	86/260 (33%)