DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14995 and Cfap410

DIOPT Version :9

Sequence 1:	NP_728935.1	Gene:	CG14995 / 38487	FlyBaseID:	FBgn0035497	Length:	454	Species:	Drosophila melanogaster
Sequence 2:	XP_006514071.1	Gene:	Cfap410 / 67884	MGIID:	1915134	Length:	271	Species:	Mus musculus

Alignment Length:	287	Identity:	98/287 - (34%)
Similarity:	142/287 - (49%)	Gaps:	54/287 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 RLTEEMVIARAKQSDLSLIKKLNCWGSDLSDVSIIKRMRGVEVLALSVNKISTLSTFEDCTKLQE 67
            :||.:||::|||.|:|..::|||||||.|:|:||.:.|..:||:.||||.:|||.....|.:|.|
Mouse     2 KLTRKMVLSRAKASELHNVRKLNCWGSQLTDISICREMPSLEVITLSVNSVSTLEPVRSCRRLSE 66

  Fly    68 LYLRKNSISDINEIAYLQNLPSLRNLWLEENPCCERAGPNYRSIVLRALPNLKKLDNVEVTQQEV 132
            ||||:|.|..:||:.||::||.||.|||.|||||..:...||..|||.||:|:||||..||::|:
Mouse    67 LYLRRNRIPSLNELFYLKDLPHLRVLWLAENPCCGTSPHLYRMTVLRNLPHLQKLDNQAVTEEEL 131

  Fly   133 EDALRGGG--VAAPEDEVYEDAYQQQQQSRRSSPQQILQQQQH--SYPQHSPPPQQQYQQQQQQQ 193
            ..||..|.  .|||..|...:...:...: .:|.....:..||  ||                .:
Mouse   132 TRALMEGDEITAAPHREGAGNGCPKPPYA-LNSVSSATETSQHLLSY----------------TE 179

  Fly   194 QQQQRGCTTPTKEPPQLP---------------SPLVKNSSEGSISHSAS-------------DL 230
            :.:.:|.||..:.|...|               ..||.....|::..:|:             |.
Mouse   180 ETEVQGQTTTDQSPSFSPRDTMRSHKNRVLNCQKALVSPHLPGTLLPAATNILTAILLLLRELDT 244

  Fly   231 YQVQAAQPLKGSQPPTPTKEPVHPPSP 257
            ..::..|...||:     .:.:|.|.|
Mouse   245 EGLETVQQTVGSR-----LQALHRPEP 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14995	NP_728935.1	leucine-rich repeat	21..42	CDD:275378	12/20 (60%)
		LRR_8	41..99	CDD:290566	30/57 (53%)
		leucine-rich repeat	43..64	CDD:275378	10/20 (50%)
		LRR_4	44..82	CDD:289563	20/37 (54%)
		LRR_RI	<56..>123	CDD:238064	35/66 (53%)
		leucine-rich repeat	65..89	CDD:275378	13/23 (57%)
		leucine-rich repeat	90..118	CDD:275378	16/27 (59%)
Cfap410	XP_006514071.1	LRR_8	19..74	CDD:338972	29/54 (54%)
		leucine-rich repeat	42..63	CDD:275382	10/20 (50%)
		LRR_9	<64..130	CDD:373143	38/65 (58%)
		leucine-rich repeat	64..87	CDD:275382	12/22 (55%)
		leucine-rich repeat	89..117	CDD:275382	16/27 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167831620
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2123
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	185	1.000	Inparanoid score	I3931
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006546
OrthoInspector	1	1.000	-	-		oto92676
orthoMCL	1	0.900	-	-		OOG6_104366
Panther	1	1.100	-	-	LDO	PTHR18849
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R8601
SonicParanoid	1	1.000	-	-		X5538
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.780