Protein Alignment CG14995 and SNRPA1

DIOPT Version :10

• Sequence 1: NP_728935.1
• Gene: CG14995 / 38487
• FlyBaseID: FBgn0035497
• Length: 454
• Species: Drosophila melanogaster
• Sequence 2: NP_003081.2
• Gene: SNRPA1 / 6627
• HGNCID: 11152
• Length: 255
• Species: Homo sapiens
• Alignment Length: 275
• Identity: 60/275 - (21%)
• Similarity: 104/275 - (37%)
• Gaps: 87/275 - (31%)

  Fly     1 MSRLTEEMVIARAKQSDLSLIKKLNCWG------------------SDLSDVSIIK-----RMRG 42
            |.:||.|::...|:.::....::|:..|                  .|.||..|.|     .:|.
Human     1 MVKLTAELIEQAAQYTNAVRDRELDLRGYKIPVIENLGATLDQFDAIDFSDNEIRKLDGFPLLRR 65

  Fly    43 VEVLALSVNKISTLSTFED----CTKLQELYLRKNSISDINEIAYLQNLPSLRNLWLEENPCCER 103
            ::.|.::.|:|..:....|    |  |.||.|..||:.::.::..|.:|.||..|.:..||...:
Human    66 LKTLLVNNNRICRIGEGLDQALPC--LTELILTNNSLVELGDLDPLASLKSLTYLSILRNPVTNK 128

  Fly   104 AGPNYRSIVLRALPNLKKLDNVEV---TQQEVEDALRGGGVAAPEDEVYEDAYQQQQQSRRSSPQ 165
              .:||..|:..:|.::.||..:|   .:||.|...:|...|....::       .::|:..:|
Human   129 --KHYRLYVIYKVPQVRVLDFQKVKLKERQEAEKMFKGKRGAQLAKDI-------ARRSKTFNP- 183

  Fly   166 QILQQQQHSYPQHSPPPQQQYQQQQQQQQQQQRGCTTPTKEPPQLPSP----LVKNSSEGSISHS 226
                                             |...||.:....|||    .:||:..     :
Human   184 ---------------------------------GAGLPTDKKKGGPSPGDVEAIKNAIA-----N 210

  Fly   227 ASDLYQVQAAQPLKG 241
            ||.|.:|:.   |||
Human   211 ASTLAEVER---LKG 222

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14995	NP_728935.1	leucine-rich repeat	21..42	CDD:275378	7/43 (16%)
		leucine-rich repeat	43..64	CDD:275378	5/24 (21%)
		PPP1R42	<44..131	CDD:455733	25/93 (27%)
		leucine-rich repeat	65..89	CDD:275378	8/23 (35%)
		leucine-rich repeat	90..118	CDD:275378	7/27 (26%)
		dnaA	211..>389	CDD:455861	12/35 (34%)
SNRPA1	NP_003081.2	LRR_9	1..175	CDD:405295	43/184 (23%)
		LRR 1	20..41		2/20 (10%)
		leucine-rich repeat	22..43	CDD:275378	2/20 (10%)
		LRR 2	43..64		5/20 (25%)
		leucine-rich repeat	44..65	CDD:275378	5/20 (25%)
		LRR 3	65..86		4/20 (20%)
		leucine-rich repeat	66..89	CDD:275378	4/22 (18%)
		LRR 4	89..110		7/22 (32%)
		leucine-rich repeat	90..114	CDD:275378	8/23 (35%)
		leucine-rich repeat	115..127	CDD:275378	4/11 (36%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	174..201		8/67 (12%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	222..255		1/1 (100%)