Protein Alignment CG14990 and TPSAB1

DIOPT Version :10

• Sequence 1: NP_647856.2
• Gene: CG14990 / 38486
• FlyBaseID: FBgn0035496
• Length: 322
• Species: Drosophila melanogaster
• Sequence 2: NP_003285.2
• Gene: TPSAB1 / 7177
• HGNCID: 12019
• Length: 275
• Species: Homo sapiens
• Alignment Length: 267
• Identity: 87/267 - (32%)
• Similarity: 130/267 - (48%)
• Gaps: 45/267 - (16%)

  Fly    55 GLVANVKVPKDYSTPGQFPWVVALFSQGKY---FGAGSLIAPEVVLTAASIVVG---KTDAEIVV 113
            |:|...:.|:     .::||.|:|...|.|   |..||||.|:.|||||. .||   |..|.:.|
Human    30 GIVGGQEAPR-----SKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAH-CVGPDVKDLAALRV 88

  Fly   114 RAGEWNTGQRSEFLPSEDRPVARVVQHREF-SYLLGANNIALLFLANPFELKSHIRTICLPSQGR 177
            :..|.:...:.:.|     ||:|::.|.:| :..:|| :||||.|..|..:.||:.|:.||....
Human    89 QLREQHLYYQDQLL-----PVSRIIVHPQFYTAQIGA-DIALLELEEPVNVSSHVHTVTLPPASE 147

  Fly   178 SFDQ-KRCLVTGWGKVAFNDENYSN--IQKKIELPMINRAQCQ----------DQLRNTRLGVSF 229
            :|.. ..|.|||||.|. |||....  ..|::::|::....|.          |.:|..|
Human   148 TFPPGMPCWVTGWGDVD-NDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVR----- 206

  Fly   230 DLPASLICAGGEKDAGDCLGDGGSALFCPMEADPSRYEQAGIVNWGIGCQEENVPAVYTNVEMFR 294
               ..::|||..: ...|.||.|..|.|.:.   ..:.|||:|:||.||.:.|.|.:||.|..:.
Human   207 ---DDMLCAGNTR-RDSCQGDSGGPLVCKVN---GTWLQAGVVSWGEGCAQPNRPGIYTRVTYYL 264

  Fly   295 DWIYEHM 301
            |||:.::
Human   265 DWIHHYV 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14990	NP_647856.2	Tryp_SPc	67..300	CDD:238113	84/252 (33%)
TPSAB1	NP_003285.2	Tryp_SPc	31..268	CDD:238113	85/261 (33%)