DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14990 and ea

DIOPT Version :9

Sequence 1:	NP_647856.2	Gene:	CG14990 / 38486	FlyBaseID:	FBgn0035496	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	NP_524362.2	Gene:	ea / 41858	FlyBaseID:	FBgn0000533	Length:	392	Species:	Drosophila melanogaster

Alignment Length:	294	Identity:	93/294 - (31%)
Similarity:	131/294 - (44%)	Gaps:	50/294 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 TENLQPDPNQVCGMSNPNGLVANVKVPKDYSTPGQFPWVVAL---FSQGK--YFGAGSLIAPEVV 96
            :.:|.|.|.| ||....|.:...:|...|     :|||:..:   .||||  :...||||:...|
  Fly   110 SNSLLPLPGQ-CGNILSNRIYGGMKTKID-----EFPWMALIEYTKSQGKKGHHCGGSLISTRYV 168

  Fly    97 LTAASIVVGK---TDAEIV-VRAGEWNT-----------GQRSEFLPSEDRPVARVVQHREFSYL 146
            :||:..|.||   ||..:. ||.|||:|           |.:....|..|.||.|.:.|.:  |:
  Fly   169 ITASHCVNGKALPTDWRLSGVRLGEWDTNTNPDCEVDVRGMKDCAPPHLDVPVERTIPHPD--YI 231

  Fly   147 LGA----NNIALLFLANPFELKSHIRTICLP----SQGRSFDQKRCLVTGWGKVAFNDENYSNIQ 203
            ..:    |:||||.||...|....:|.||||    .:..:||.....|.||||.  ...:.||::
  Fly   232 PASKNQVNDIALLRLAQQVEYTDFVRPICLPLDVNLRSATFDGITMDVAGWGKT--EQLSASNLK 294

  Fly   204 KKIELPMINRAQCQDQLRNTRLGVSFDLPASLICAGGEKDAGDCLGDGGSALFCPMEADPSR--- 265
            .|..:......:||    |........|..:.:||||::....|.||.|..|   :..|.::
  Fly   295 LKAAVEGFRMDECQ----NVYSSQDILLEDTQMCAGGKEGVDSCRGDSGGPL---IGLDTNKVNT 352

  Fly   266 -YEQAGIVNWG-IGCQEENVPAVYTNVEMFRDWI 297
             |..||:|::| ..|.....|.|||.|..:.|||
  Fly   353 YYFLAGVVSFGPTPCGLAGWPGVYTLVGKYVDWI 386

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14990	NP_647856.2	Tryp_SPc	67..300	CDD:238113	84/264 (32%)
CG14990	NP_647856.2	Tryp_SPc	67..297	CDD:214473	82/262 (31%)
ea	NP_524362.2	CLIP	37..89	CDD:288855
		Tryp_SPc	127..386	CDD:214473	84/274 (31%)
		Tryp_SPc	128..389	CDD:238113	86/275 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45457487
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24256
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940