DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14990 and l(2)k05911

DIOPT Version :9

Sequence 1:	NP_647856.2	Gene:	CG14990 / 38486	FlyBaseID:	FBgn0035496	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	NP_723797.3	Gene:	l(2)k05911 / 34731	FlyBaseID:	FBgn0284244	Length:	639	Species:	Drosophila melanogaster

Alignment Length:	268	Identity:	92/268 - (34%)
Similarity:	132/268 - (49%)	Gaps:	30/268 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 CGMSNP-----NGLVANVKVPKDYSTPGQFPWVVALFSQGKYFGAGSLIAPEVVLTAASIVVGKT 107
            ||..||     ..:|..:.     ::|.:|||:..||..||.|..||||....:||||..|...|
  Fly   387 CGNKNPVTPDQERIVGGIN-----ASPHEFPWIAVLFKSGKQFCGGSLITNSHILTAAHCVARMT 446

  Fly   108 D---AEIVVRAGEWNTGQRSEFLPSEDRPVARVVQHREFSYLLGANNIALLFLANPFELKSHIRT 169
            .   |.:....|::|.|...| :....|.:.|:|:|:.|.:....|::|:|.|:.|......|:.
  Fly   447 SWDVAALTAHLGDYNIGTDFE-VQHVSRRIKRLVRHKGFEFSTLHNDVAILTLSEPVPFTREIQP 510

  Fly   170 ICLPS----QGRSFDQKRCLVTGWGKVAFNDENYSNIQKKIELPMINRAQCQDQLRNTRLGVSFD 230
            ||||:    |.||:..:...|.|||.:..|....|.:| |:::|:...|:|..:......|   .
  Fly   511 ICLPTSPSQQSRSYSGQVATVAGWGSLRENGPQPSILQ-KVDIPIWTNAECARKYGRAAPG---G 571

  Fly   231 LPASLICAG-GEKDAGDCLGDGGSALFCPMEA-DPSRYEQAGIVNWGIGCQEENVPAVYTNVEMF 293
            :..|:|||| ..||:  |.||.|.    ||.. |..||.|.|||:|||||.:...|.|||.|...
  Fly   572 IIESMICAGQAAKDS--CSGDSGG----PMVINDGGRYTQVGIVSWGIGCGKGQYPGVYTRVTSL 630

  Fly   294 RDWIYEHM 301
            ..|||:::
  Fly   631 LPWIYKNI 638

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14990	NP_647856.2	Tryp_SPc	67..300	CDD:238113	87/241 (36%)
CG14990	NP_647856.2	Tryp_SPc	67..297	CDD:214473	84/238 (35%)
l(2)k05911	NP_723797.3	CLIP	111..174	CDD:197829
		Tryp_SPc	399..634	CDD:214473	85/250 (34%)
		Tryp_SPc	400..637	CDD:238113	88/252 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24256
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010