Protein Alignment CG14990 and PRSS50

DIOPT Version :10

• Sequence 1: NP_647856.2
• Gene: CG14990 / 38486
• FlyBaseID: FBgn0035496
• Length: 322
• Species: Drosophila melanogaster
• Sequence 2: NP_037402.1
• Gene: PRSS50 / 29122
• HGNCID: 17910
• Length: 385
• Species: Homo sapiens
• Alignment Length: 349
• Identity: 94/349 - (26%)
• Similarity: 154/349 - (44%)
• Gaps: 60/349 - (17%)

  Fly    11 LLVSFLCSATGQNEGGAPGIFNGMS-FTENLQPDPNQVCGMSNPNGL------------------ 56
            ||:..|.||.....|.|||..:... ..:::|..|...|..|.|..|
Human    27 LLLLLLRSAGCWGAGEAPGALSTADPADQSVQCVPKATCPSSRPRLLWQTPTTQTLPSTTMETQF 91

  Fly    57 -VANVKVPKDYSTPG-----------------QFPWVVALFSQGKYFGAGSLIAPEVVLTAASIV 103
             |:..|| ..|.:.|                 ::||:|::.:.|.:..||::||.:.|||.|..:
Human    92 PVSEGKV-DPYRSCGFSYEQDPTLRDPEAVARRWPWMVSVRANGTHICAGTIIASQWVLTVAHCL 155

  Fly   104 VGKTDAEIVVRAGEWNTGQRSEFLPSEDRPVARVVQH------REFSYLLGANNIALLFLANPFE 162
            :.: |....||.|.....|.::  .:.|.||.:|:.|      |.:|::..||:|.||.|....:
Human   156 IWR-DVIYSVRVGSPWIDQMTQ--TASDVPVLQVIMHSRYRAQRFWSWVGQANDIGLLKLKQELK 217

  Fly   163 LKSHIRTICLPSQGRSF---DQKRCLVTGWG--KVAFNDENYSNIQKKIELPMINRAQCQDQLRN 222
            ..:::|.||||  |..:   |..||.|||||  |.......:..||:| |:.::|..:|.:...|
Human   218 YSNYVRPICLP--GTDYVLKDHSRCTVTGWGLSKADGMWPQFRTIQEK-EVIILNNKECDNFYHN 279

  Fly   223 -TRLGVSFD-LPASLICAGGEKDAGDCLGDGGSALFCPMEADPSRYEQAGIVNWGIGCQEENVPA 285
             |::..... :.:.::||........|....|..|.|.||   ..:...|:|:||.|||:...|.
Human   280 FTKIPTLVQIIKSQMMCAEDTHREKFCYELTGEPLVCSME---GTWYLVGLVSWGAGCQKSEAPP 341

  Fly   286 VYTNVEMFRDWIYEHMAQNSNSVP 309
            :|..|..::.||::.:...:.::|
Human   342 IYLQVSSYQHWIWDCLNGQALALP 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14990	NP_647856.2	Tryp_SPc	67..300	CDD:238113	74/262 (28%)
PRSS50	NP_037402.1	Tryp_SPc	118..353	CDD:238113	71/243 (29%)