DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14990 and si:dkey-32n7.7

DIOPT Version :9

Sequence 1:	NP_647856.2	Gene:	CG14990 / 38486	FlyBaseID:	FBgn0035496	Length:	322	Species:	Drosophila melanogaster
Sequence 2:	XP_021335883.1	Gene:	si:dkey-32n7.7 / 108191692	ZFINID:	ZDB-GENE-121214-179	Length:	609	Species:	Danio rerio

Alignment Length:	271	Identity:	82/271 - (30%)
Similarity:	128/271 - (47%)	Gaps:	49/271 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 VCG---MSNPNGLVANVKVPKDYSTPGQFPWVVALFSQGKYFGAGSLIAPEVVLTAASIVVGKTD 108
            |||   :::.||.|..     ..|:...:||..:|:........||||..|.||:||....|:
Zfish   296 VCGIIPVNSSNGTVGG-----QNSSAVHWPWQASLYWYSGQTCGGSLINKEWVLSAAHCFNGQ-- 353

  Fly   109 AEIVVRAGEWNT---GQRSE--FLPSE-DRPVARVVQHREFSYLLGANNIALLFLANPFELKSHI 167
                 |.|.:.|   |.:::  :.||. .|.|..|::|..::.....|:|||:.|:.|......|
Zfish   354 -----RNGFYLTVILGPKTQNKYDPSRISRSVKAVIKHPYYNPNTNDNDIALVRLSFPITFTDSI 413

  Fly   168 RTICLPSQGRSFD-QKRCLVTGWGKVAFNDENYSN--------IQKKIELPMINRAQCQDQLRNT 223
            |.:||.::|..|: .....:|.|       .|.|:        |.:::|:|:|...||     |.
Zfish   414 RPVCLAAEGSVFNSDTESWITTW-------RNISDGVPLPSPKIFQEVEVPVIGNRQC-----NC 466

  Fly   224 RLGVSFDLPASLICAGGEKDAGD-CLGDGGSALFCPMEADPSR-YEQAGIVNWGIGCQEENVPAV 286
            ..||. .:..::||||..|:..| |.||.|.    ||.::.|. :.|:|||::|.||.:...|.|
Zfish   467 LYGVG-SITDNMICAGLLKEGKDLCQGDSGG----PMVSNQSSVWVQSGIVSFGSGCAQSEFPGV 526

  Fly   287 YTNVEMFRDWI 297
            ||.|..:::||
Zfish   527 YTRVSRYQEWI 537

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14990	NP_647856.2	Tryp_SPc	67..300	CDD:238113	76/248 (31%)
CG14990	NP_647856.2	Tryp_SPc	67..297	CDD:214473	74/246 (30%)
si:dkey-32n7.7	XP_021335883.1	NIDO	4..63	CDD:310601
		NIDO	141..272	CDD:322035
		Tryp_SPc	309..537	CDD:238113	75/256 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170587614
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930