Protein Alignment Gad1 and GAD1

DIOPT Version :10

• Sequence 1: NP_523914.2
• Gene: Gad1 / 38484
• FlyBaseID: FBgn0004516
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: NP_013976.1
• Gene: GAD1 / 855291
• SGDID: S000004862
• Length: 585
• Species: Saccharomyces cerevisiae
• Alignment Length: 517
• Identity: 97/517 - (18%)
• Similarity: 181/517 - (35%)
• Gaps: 138/517 - (26%)

  Fly    39 KVIDVLLDFVKATNDRNEKVLDFHHPEDMKRLLD---------LDVPDRALPLQ---QLIEDCAT 91
            ||:..|......:||..:..:...| :....:.|         ..||.:.||..   |||.:..|
Yeast    18 KVVHDLAGLQLLSNDVQKSAVQSGH-QGSNNMRDTSSQGMANKYSVPKKGLPADLSYQLIHNELT 81

  Fly    92 TLKYQVKTGHPHFFNQLSNGLDLISMAGEWLTATA--------NTNMFTYEIAPVFILMENVVLT 148
            .      .|:||        |:|.|....:.|..|        ..|:...:..|..|.:....::
Yeast    82 L------DGNPH--------LNLASFVNTFTTDQARKLIDENLTKNLADNDEYPQLIELTQRCIS 132

  Fly   149 KMREIIGW-------------SGGDSILAPGGSISNLYAFLAARHKMFPNYKEHGSVGLPGTLVM 200
            .:.::  |             :|....:..||        ||.:.:.....|..|.......::|
Yeast   133 MLAQL--WHANPDEEPIGCATTGSSEAIMLGG--------LAMKKRWEHRMKNAGKDASKPNIIM 187

  Fly   201 FTSDQCHYSIKSCAAVCGLGTDHCIVVP-SDEHGKMITSELERLILERKAKGDIPFFVNATAGTT 264
              |..|..:::.......:   .|.:|| |.....|:..|   .:.:...:..|..||  ..|||
Yeast   188 --SSACQVALEKFTRYFEV---ECRLVPVSHRSHHMLDPE---SLWDYVDENTIGCFV--ILGTT 242

  Fly   265 VLGAFDDINTIADICQ----KYNCW------MHIDAAWGGGLL-MSRKHRHPRFTGVE------- 311
            ..|..:::..:||:..    |:..|      :|.|.|.||.:: ...:..|.:..|:|
Yeast   243 YTGHLENVEKVADVLSQIEAKHPDWSNTDIPIHADGASGGFIIPFGFEKEHMKAYGMERWGFNHP 307

  Fly   312 RADSVTWNPHKL------MGALLQCSTIHFKEDGLLISCNQMSAEYLFMTDKQYDISYD-TGDKV 369
            |..|:..:.||.      :|.:|      ::::.||....:...:||...::.:.:::. .|.:|
Yeast   308 RVVSMNTSGHKFGLTTPGLGWVL------WRDESLLADELRFKLKYLGGVEETFGLNFSRPGFQV 366

  Fly   370 IQCGRHNDIFKLWLQWRAKGTEGFEQQ-QDRLMELVQYQLKRIR--------EQSDRFHLILE-- 423
            :    |.     :..:.:.|..|:..| |:.|.....:..:.:.        |.....|..:|
Yeast   367 V----HQ-----YFNFVSLGHSGYRTQFQNSLFVARAFSFELLNSSKLPGCFEIVSSIHESIEND 422

  Fly   424 --PECVNVSFWYVPKRLR-GVP----------HDAKKEVELGKICPIIKGRMMQKGTLMVGY 472
              |:.|. .:|..|:..: |||          |:...||....:..:::||    |.::..|
Yeast   423 SAPKSVK-DYWEHPQAYKPGVPLVAFKLSKKFHEEYPEVPQAILSSLLRGR----GWIIPNY 479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gad1	NP_523914.2	Pyridoxal_deC	64..434	CDD:395219	80/441 (18%)
GAD1	NP_013976.1	Glu-decarb-GAD	41..522	CDD:130848	92/494 (19%)